DZI19-36: Case 5

UMass: Unusual B- and T-cell Lymphoproliferative Disorders • (DZI19-36)

Clinical

73-year-old man with nodular lesions of left thigh leading to left leg swelling and edema. Found to have a large left groin lymph node on exam, which was biopsied. Staging PET/CT revealed multiple FDG-avid enlarged lymph nodes above and below diaphragm, along with FDG-avid subcutaneous nodules of left thigh.

Diagnosis

Anaplastic large cell lymphoma, ALK-negative

References

• Savage et al. ALK- anaplastic large-cell lymphoma is clinically and immunophenotypically different from both ALK+ ALCL and peripheral

T-cell lymphoma, NOS. Blood 2008;111:5496-504. PubMed ID:18385450

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UMass: Unusual B- and T-cell Lymphoproliferative Disorders • Dr. Sohani

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