DZI19-36: Case 6

UMass: Unusual B- and T-cell Lymphoproliferative Disorders • (DZI19-36)

Clinical

53-year-old woman with history of right breast cancer 17 years prior, status post mastectomy and reconstructive surgery with bilateral silicone implants. Now with seroma around left breast for about 1 year. Seroma fluid aspirated and implant removed. Tissue from around the implant submitted for microscopic examination.

Diagnosis

Breast-implant associated anaplastic large cell lymphoma

References

• Aladily TN, et al. Anaplastic large cell lymphoma associated with breast implants: a report of 13 cases. Am J Surg Pathol 2012;36:1000-8. PubMed ID:22613996
• Miranda RN, et al. Breast implant-associated anaplastic large-cell lymphoma: long-term follow-up of 60 patients. J Clin Oncol 2014;32:114-20. PubMed ID:24323027

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UMass: Unusual B- and T-cell Lymphoproliferative Disorders • Dr. Sohani

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