Difference between revisions of "DZI19-36-Case-1"
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| − | |clinical_hx=64-year-old woman with history of lupus on methotrexate, with prominent bilateral cervical and axillary lymphadenopathy (biopsy is of enlarged right axillary lymph node). Serum and urine protein and immunofixation electrophoresis showed abnormal banding (images of gels provided). | + | |clinical_hx=64-year-old woman with history of lupus on methotrexate, with prominent bilateral cervical and axillary lymphadenopathy (biopsy is of enlarged right axillary lymph node). Serum and urine protein and immunofixation electrophoresis showed abnormal banding (images of gels provided). |
|case_diagnosis=Gamma heavy chain disease | |case_diagnosis=Gamma heavy chain disease | ||
| + | |publish_timestamp=2019/06/28 13:00 | ||
| + | |publish_diagnosis=2019/04/19 | ||
| + | |publish_references=2019/04/19 | ||
}} | }} | ||
{{dziSlide | {{dziSlide | ||
|order_date=April 03, 2019 04:46:35 PM | |order_date=April 03, 2019 04:46:35 PM | ||
|user=Sac11 | |user=Sac11 | ||
| + | |slide_stain=H&E | ||
| + | }} | ||
| + | {{dziReference | ||
| + | |order_date=April 17, 2019 11:33:38 AM | ||
| + | |user=Em99 | ||
| + | |reference_text=Bianchi G, et al. The heavy chain diseases: clinical and pathologic features. Oncology (Williston Park) 2014;28:45-53. | ||
| + | |pubmed=24683718 | ||
| + | }} | ||
| + | {{dziReference | ||
| + | |order_date=April 17, 2019 11:33:38 AM | ||
| + | |user=Em99 | ||
| + | |reference_text=Bieliauskas S, et al. Gamma heavy-chain disease: defining the spectrum of associated lymphoproliferative disorders through analysis of 13 cases. Am J Surg Pathol 2012;36:534-43. | ||
| + | |pubmed=22301495 | ||
| + | }} | ||
| + | {{dziReference | ||
| + | |order_date=April 17, 2019 11:33:38 AM | ||
| + | |user=Em99 | ||
| + | |reference_text=Hamadeh F, et al. Gamma heavy chain disease lacks the MYD88 L265p mutation associated with lymphoplasmacytic lymphoma. Haematologica 2014;99:e154-5. | ||
| + | |pubmed=24859878 | ||
| + | }} | ||
| + | {{dziMedia | ||
| + | |order_date=April 09, 2019 11:43:40 PM | ||
| + | |user=Em99 | ||
| + | |media_filename=DZI19-36-Case-1 SPEP UPEP IFE.JPG | ||
| + | |media_text=SPEP | ||
}} | }} | ||
Latest revision as of 15:06, March 9, 2022
| UMass: Unusual B- and T-cell Lymphoproliferative Disorders • (DZI19-36) |
Clinical
64-year-old woman with history of lupus on methotrexate, with prominent bilateral cervical and axillary lymphadenopathy (biopsy is of enlarged right axillary lymph node). Serum and urine protein and immunofixation electrophoresis showed abnormal banding (images of gels provided).
Diagnosis
Gamma heavy chain disease
References
- Hamadeh F, et al. Gamma heavy chain disease lacks the MYD88 L265p mutation associated with lymphoplasmacytic lymphoma. Haematologica 2014;99:e154-5. PubMed ID:24859878
- Bianchi G, et al. The heavy chain diseases: clinical and pathologic features. Oncology (Williston Park) 2014;28:45-53. PubMed ID:24683718
- Bieliauskas S, et al. Gamma heavy-chain disease: defining the spectrum of associated lymphoproliferative disorders through analysis of 13 cases. Am J Surg Pathol 2012;36:534-43. PubMed ID:22301495
Additional files
SPEP
Slide: 1
Stain: H&E • File: DZI19-36-Case-1_1
UMass: Unusual B- and T-cell Lymphoproliferative Disorders • Dr. Sohani
