WSI23-10: Hematopathology didactic - Thursday, April 6, 2023

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Request type AP didactic (PGY2+) - MGH
Subspecialty Hematopathology
Topic Dartmouth Slide Session
Presenter Hasserjian, Robert P.,MD
Date and time Thursday, April 6, 2023 12:00 AM



Case Clinical history Requester
Case Clinical history Requester

Case 1


56 year-old man with history of MDS now with dropping blood counts. WBC 4.94 (63% polys 32% lymphs 1% atypical lymphs 4% monos 0% blasts) HGB 7.3 MCV 89 PLT 60. Rh27

Case 2


30 year-old man with history of juvenile rheumatoid arthritis treated with methotrexate 10 years ago now with severe anemia. WBC 2.3 HGB 6.4 MCV 95.6 PLT 11. Bone marrow biopsy and peripheral blood smear provided (no aspirate was obtainable due to 'dry tap'). Rh27

Case 3


53 year-old man with cytopenias and splenomegaly. WBC 10.77 (49% polys 44% lymphs 7% monos). HGB 7.9 PLT 46. Rh27

Case 4


60 year old man presented with fatigue found to have marked leukocytosis. WBC 71.2 (67% polys 5% lymphs 6% monos 11% eos 4% basos 2% bands 1% myelos 3% metas 2% promyelocytes 1 nRBC/100 WBC) HGB 7.0 MCV 105.8 PLT 56. Biopsy aspirate and peripheral smear provided. Rh27

Case 5


79 year-old man with AML status-post treatment persistent low blood counts. WBC 1.0 (56% polys 44% lymphs) HGB 7.7 MCV 89.4 PLT 19. Rh27

Case 6


32 year-old woman with anemia. WBC 4.1 (59% polys 29% lymphs 12% monos) HGB 10.4 MCV 86.9 PLT 235. Rh27

Case 7


68 year old man with history of MDS on luspatercept. Aja51