DZI19-121-Case-1

DZI19-121-Case-1

63 year old woman with a history of breast CA s/p bilateral mastectomy presents with difficulty walking, staggering gait, and fatigue

Integrated diagnosis: GLIOBLASTOMA, IDH-WILDTYPE

Histological diagnosis: Glioblastoma

WHO histological grade: IV

Molecular information: IDH1: negative (R132H immunohistochemistry) MGMT promoter: methylated (methylation specific PCR)

IHC for mutant ID1(R132H) was negative and is sufficient in patients >55 years of age to determine IDH status (rare to find non-canonical mutations in this group).

December 31, 1969 7:00:00 PM