Difference between revisions of "DZI19-175"
From MGH Learn Pathology
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|supportingInfo=Gastrointestinal | |supportingInfo=Gastrointestinal | ||
|reasonCode=Dr. Nardi -Molecular Pathology Slide Sessions | |reasonCode=Dr. Nardi -Molecular Pathology Slide Sessions | ||
| − | |subject= | + | |subject=MGH |
| − | |performer= | + | |performer=VN048 |
|authoredOn=October 24, 2019 03:03:40 PM | |authoredOn=October 24, 2019 03:03:40 PM | ||
|requester=Sac11 | |requester=Sac11 | ||
| + | |access=public | ||
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{{status | {{status | ||
Latest revision as of 15:11, June 21, 2022
Request details
- Request type Cme
- Subspecialty Gastrointestinal
- Set CCSP 2019
- Topic Dr. Nardi -Molecular Pathology Slide Sessions
- Presenter Nardi, Valentina,MD
| Case | Clinical history | Requester |
|---|---|---|
| Case | Clinical history | Requester |
|
| 83 yo woman with leukocytosis (WBC: 50; 75% polys) • mild anemia (HB 11.4; HCT: 36%) and thrombocytopenia (PLT: 109). Peripheral blood and bone marrow biopsy (HE & Giemsa). What is the differential diagnosis? | Sac11 |
|
| 55 yo man with history of Ewing sarcoma. Now decreasing WBC and bony lesions. Bone marrow biopsy. The neoplastic cells are CD45– (maybe rare cells staining?) • keratin - • CD34- CD117- MPO- CD56- CD19- CD20- TdT- CD64- CD33- CD13- CD138- lysozyme- FLI-1- CD99+. What is your diagnosis? | Sac11 |
|
| 20-month old boy with splenomegaly • thrombocytosis • severe anemia and peripheral blasts
WBC: 29.6; HGB: 4.7; HCT: 13.4%; MCV: 85.9 fL; PLT: 900 (Diff: 36% polys; 30% lymphs; 12% monos; 6% eos; 2% basos; 1% myelocytes; 13% blasts; 12 nRBCs/100WBC). Peripheral blood smear. What is your differential diagnosis? Two days later • after RBCs and fluids: WBC: 8.1; HGB: 9.2; HCT: 25.2; MCV: 85 fL; PLT: 250 (Diff: 47% polys; 29% lymphs; 7% monos; 8% blasts; 7% eos; 2% basos; 2% metas Bone marrow biopsy (HE • reticulin stain) and touch prep (clot). What is your differential diagnosis? | Sac11 |
|
| 39 yo man with fatigue • chills • back pain & anemia (WBC 4.5; HGB 10.2; HCT 32.2; MCV: 85.4; PLT: 330; Normal
differential) Workup included imaging which showed a T9 sclerotic lesion • diffuse bony infiltration • enlarged cervical nodes. Bone marrow biopsy and lymph node biopsy. What are your diagnosis? | Sac11 |
|
| 23 yo man with CML in chronic phase now with increasing circulating blastsWBC 50; HGB 11.2; HCT 32.2; MCV: 85.4; PLT: 330 Diff: 42% polys; 11% metas; 3% promyelocytes: 17% basos; 6% eos; 8% blasts; 13% lymphs.Peripheral blood smear • bone marrow biopsy and aspirate smear
| Sac11 |
