23 yo man with CML in chronic phase now with increasing circulating blastsWBC 50; HGB 11.2; HCT 32.2; MCV: 85.4; PLT: 330 Diff: 42% polys; 11% metas; 3% promyelocytes: 17% basos; 6% eos; 8% blasts; 13% lymphs.Peripheral blood smear, bone marrow biopsy and aspirate smear
Is it still CML chronic phase or is it accelerated phase?
Chronic myeloid leukemia, BCR-ABL1+, in myeloid blast crisis (followed by lymphoid blast crisis)