Difference between revisions of "WSI21-136"

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Latest revision as of 09:56, July 7, 2023


Request type Study
Subspecialty Cytology
Set Cytology
Topic Cerebrospinal Fluid
Presenter MGH


Toggle columns: Diagnosis

Case Clinical history Requester Diagnosis
Case Clinical history Requester Diagnosis

Case 1


74-year-old female. History of metastatic breast carcinoma and ventricular shunt placement. Iac0 Brain parenchyma.

Case 2


67yo F w/history of metastatic lung adenocarcinoma Mlz8 Metastatic adenocarcinoma

Case 3


59 year old man with multiple sclerosis on high dose dexamethasone Lz17 Fungal forms consistent with Cryptococcus neoformans. Narrow based budding yeast (do not mistake for RBCs).

Case 4


66 year old M with history of a spine cord lesion and suspicion for Lyme's disease Lcm51 Lyme's disease pleocytosis

Case 5


67 year old male with mental status changes and ring enhancing lesions in the parietal lobe. Cfh13 No malignant cells identified. Cryptococcus.

Case 6


76 year-old man with a history of CLL and symptoms concerning for new CNS involvement. Cfh13 Positive for malignant cells with clonal B cell population on flow cytometry. Clonal B cell population and large malignant cells of unclear etiology. Concurrent surgical specimen: DLBCL consistent with Richter's transformation of patient's known CLL.

Case 7


66 yo F with a history of high grade B cell lymphoma. Cfh13 No malignant cells identified. Chondrocytes.

Case 8


25 yo M with a history of medulloblastoma status post resection. Cfh13 Poorly differentiated round cell malignancy. IHC on subsequent biopsy confirmed recurrent/residual medulloblastoma.

Case 9


37 yo woman with a history of melanoma Cfh13 Metastatic melanoma.

Case 10


65 yo F with NSCLC Ndk6 Adenocarcinoma • consistent with metastasis from patient's known lung primary.

Case 11


67 yo M with known metastatic prostate cancer Ndk6 Metastatic adenocarcinoma • cytomorphologically consistent with the patient’s known prostate primary

Case 12


59 yo M with a history of AML Ndk6 Blasts present • consistent with involvement by the patient's known leukemia.

Case 13


48 yo M with a history of adenocarcinoma • lung primary. Ndk6 Metastatic adenocarcinoma

Case 14


74yo F with history of lung cancer who presents with acute and chronic intractable nausea and vomiting Ndk6 Adenocarcinoma • consistent with metastasis of the patient's known lung primary.

Case 15


66 yo M with a history of transformed follicular lymphoma and CAR-T on trial. Ndk6 Positive for malignancy • c/w patient's know transformed follicular lymphoma

Case 16


57 yo M with a history mantle cell lymphoma and known CNS involvement. Ndk6 Positive for malignant cells • compatible with involvement by mantle cell lymphoma

Case 17


57 year old male with history of GBM Ndk6 Malignant neoplasm • consistent with patient’s known glioblastoma

Case 18


69 YO F with history of B cell lymphoma Ndk6 Negative for Malignancy- Abundant acute inflammation • rare lymphocytes and monocytes

Case 19


49 yo F with altered mental status • convulsions • and history of high grade serous carcinoma Ndk6 POSITIVE FOR MALIGNANT CELLS- Adenocarcinoma with focally micropapillary and signet ring cell morphology.

Case 139


54 yo F with metastatic breast cancer • leptomeningeal disease suspected Ndk6 Carcinoma • consistent with metastasis from patient's known high-grade breast cancer

Case 140


74-year-old man with lytic bone lesions Lt511 Plasma cell neoplasm

Case 141


48F with met pancreas cancer with ?LMD Ndk6 Metastatic adenocarcinoma

Case 142


76 yo F history of metastatic lung adenocarcinoma • now presenting with new CNS involvement Ndk6 Metastatic adenocarcinoma






















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