WSI21-136-Case-5

Sequence	Case	Clinical history	Diagnosis
1	WSI21-136-Case-1 WSI21-136-Case-1	74-year-old female. History of metastatic breast carcinoma and ventricular shunt placement. 74-year-old female. History of metastatic breast carcinoma and ventricular shunt placement.	Brain parenchyma. Brain parenchyma.
2	WSI21-136-Case-2 WSI21-136-Case-2	67yo F w/history of metastatic lung adenocarcinoma 67yo F w/history of metastatic lung adenocarcinoma	Metastatic adenocarcinoma Metastatic adenocarcinoma
3	WSI21-136-Case-3 WSI21-136-Case-3	59 year old man with multiple sclerosis on high dose dexamethasone 59 year old man with multiple sclerosis on high dose dexamethasone	Fungal forms consistent with Cryptococcus neoformans. Narrow based budding yeast (do not mistake for RBCs). Fungal forms consistent with Cryptococcus neoformans. Narrow based budding yeast (do not mistake for RBCs).
4	WSI21-136-Case-4 WSI21-136-Case-4	66 year old M with history of a spine cord lesion and suspicion for Lyme's disease 66 year old M with history of a spine cord lesion and suspicion for Lyme's disease	Lyme's disease pleocytosis Lyme's disease pleocytosis
5	WSI21-136-Case-5 WSI21-136-Case-5	67 year old male with mental status changes and ring enhancing lesions in the parietal lobe. 67 year old male with mental status changes and ring enhancing lesions in the parietal lobe.	No malignant cells identified. Cryptococcus. No malignant cells identified. Cryptococcus.
6	WSI21-136-Case-6 WSI21-136-Case-6	76 year-old man with a history of CLL and symptoms concerning for new CNS involvement. 76 year-old man with a history of CLL and symptoms concerning for new CNS involvement.	Positive for malignant cells with clonal B cell population on flow cytometry. Clonal B cell population and large malignant cells of unclear etiology. Concurrent surgical specimen: DLBCL consistent with Richter's transformation of patient's known CLL. Positive for malignant cells with clonal B cell population on flow cytometry. Clonal B cell population and large malignant cells of unclear etiology. Concurrent surgical specimen: DLBCL consistent with Richter's transformation of patient's known CLL.
7	WSI21-136-Case-7 WSI21-136-Case-7	66 yo F with a history of high grade B cell lymphoma. 66 yo F with a history of high grade B cell lymphoma.	No malignant cells identified. Chondrocytes. No malignant cells identified. Chondrocytes.
8	WSI21-136-Case-8 WSI21-136-Case-8	25 yo M with a history of medulloblastoma status post resection. 25 yo M with a history of medulloblastoma status post resection.	Poorly differentiated round cell malignancy. IHC on subsequent biopsy confirmed recurrent/residual medulloblastoma. Poorly differentiated round cell malignancy. IHC on subsequent biopsy confirmed recurrent/residual medulloblastoma.
9	WSI21-136-Case-9 WSI21-136-Case-9	37 yo woman with a history of melanoma 37 yo woman with a history of melanoma	Metastatic melanoma. Metastatic melanoma.
10	WSI21-136-Case-10 WSI21-136-Case-10	65 yo F with NSCLC 65 yo F with NSCLC	Adenocarcinoma, consistent with metastasis from patient's known lung primary. Adenocarcinoma, consistent with metastasis from patient's known lung primary.

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