WSI21-138

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Request type Study

Subspecialty Cytology

Set Cytology

Topic Breast

Presenter MGH

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Toggle columns: Diagnosis

Case	Clinical history	Requester	Diagnosis
Case	Clinical history	Requester	Diagnosis
Case 1	68-year-old female. 2-cm breast mass.	Iac0	Ductal carcinoma with mucinous features.
Case 2	19F • palpable firm ovoid 2.0 x 1.5 cm mobile nodule in left breast at 3:00 at 3 cm from the areola. No imaging performed.	Ai293	Fibroadenoma. - Complex branching groups of proliferative appearing ductal epithelial cells with associated myoepithelial cells. - Abundant naked stromal nuclei in background. - Few fragments of more or less dense fibrous stroma • rarely delicate specialized stroma.
Case 3	52 YO female with right breast mass	Ndk6	Adenocarcinoma
Case 4	41 YO female with breast mass and suspicious mammogram	Ndk6	Ductal carcinoma with papillary and high grade nuclear features
Case 5	41 YO female with breast mass	Ndk6	Negative for malignancy- consistent with fibroadenoma
Case 6	71 YO female s/p excision and XRT for DCIS. Now presenting with hard • ill-defined nodule in tail of breast.	Ndk6	Ductal carcinoma
Case 7	60 YO female s/p mastectomy with nodule in right lateral breast flap	Ndk6	Negative for malignancy- abundant debris • fibroadipose tissue • and numerous macrophages • including multinucleate forms c/w fat necrosis
Case 8	48 YO female with self discovered mass at 11:00 left breast measuring 3 cm	Ndk6	Ductal carcinoma
Case 9	33 YO female with suspicious left breast mass	Ndk6	High grade ductal carcinoma with extensive necrosis
Case 10	49 YO female with solid breast lump	Ndk6	Adenocarcinoma • high grade • with calcifications
Case 11	74 years old woman with 10 mm cyst in the left breast	Lt511	Apocrine cyst
Case 12	73 yo f s/p breast cancer. New multiple red raised papules left breast • 0.4 - 0.8 cm.	Ndk6	Malignant neoplasm • suggestive of angiosarcoma. Note: Immunostains for CD31 • CD34 • factor VIII • FLI-1. AE1.3 / CAM5.2 • high molecular weight keratin and D240 were examined; the findings support the above diagnosis.
Case 13	82 yo f w/ hard 4 cm mass	Ndk6	Ductal Carcinoma with abundant mucin production
Case 14	67 yo f w/ solid breast lesion	Ndk6	Medullary Carcinoma Large anaplastic cells with giant nucleoli • numerous stripped malignant nuclei • scattered lymphocytes • and necrosis
Case 15	68 yo m w/ breast mass	Ndk6	Ductal Carcinoma
Case 16	59 yo f w/ history of melanoma	Ndk6	Consistent with metastatic melanoma
Case 17	25 yo f w/ unchanged breast nodule for years	Ndk6	Fibroadenoma
Case 18	88 yo f w/ a 4.3 cm breast mass	Ndk6	Poorly differentiated carcinoma Resection diagnosis: Metaplastic carcinoma • invasive • grade 3/3 with <50% ductal differentiation and 95% non-specific mesenchymal differentiation (polygonal • round • and spindle cells)
Case 139	48 yo F w/ seroma. R/o ALCL.	Ndk6	Negative for malignancy- proteinaceous debris with small amount of admixed blood
Case 140	46 yo F w/ breast cyst	Ndk6	No malignant cells identified- Abundant foamy histiocytes consistent with cyst contents