WSI21-138: Breast
From MGH Learn Pathology
Toggle columns: Diagnosis
| Case | Clinical history | Requester | Diagnosis |
|---|---|---|---|
| Case | Clinical history | Requester | Diagnosis |
|
| 68-year-old female. 2-cm breast mass. | Iac0 | Ductal carcinoma with mucinous features. |
|
| 19F • palpable firm ovoid 2.0 x 1.5 cm mobile nodule in left breast at 3:00 at 3 cm from the areola. No imaging performed. | Ai293 | Fibroadenoma.
- Complex branching groups of proliferative appearing ductal epithelial cells with associated myoepithelial cells. - Abundant naked stromal nuclei in background. - Few fragments of more or less dense fibrous stroma • rarely delicate specialized stroma. |
|
| 52 YO female with right breast mass | Ndk6 | Adenocarcinoma |
|
| 41 YO female with breast mass and suspicious mammogram | Ndk6 | Ductal carcinoma with papillary and high grade nuclear features |
|
| 41 YO female with breast mass | Ndk6 | Negative for malignancy- consistent with fibroadenoma |
|
| 71 YO female s/p excision and XRT for DCIS. Now presenting with hard • ill-defined nodule in tail of breast. | Ndk6 | Ductal carcinoma |
|
| 60 YO female s/p mastectomy with nodule in right lateral breast flap | Ndk6 | Negative for malignancy- abundant debris • fibroadipose tissue • and numerous macrophages • including multinucleate forms c/w fat necrosis |
|
| 48 YO female with self discovered mass at 11:00 left breast measuring 3 cm | Ndk6 | Ductal carcinoma |
|
| 33 YO female with suspicious left breast mass | Ndk6 | High grade ductal carcinoma with extensive necrosis |
|
| 49 YO female with solid breast lump | Ndk6 | Adenocarcinoma • high grade • with calcifications |
|
| 74 years old woman with 10 mm cyst in the left breast | Lt511 | Apocrine cyst |
|
| 73 yo f s/p breast cancer. New multiple red raised papules left breast • 0.4 - 0.8 cm. | Ndk6 | Malignant neoplasm • suggestive of angiosarcoma. Note: Immunostains for CD31 • CD34 • factor VIII • FLI-1. AE1.3 / CAM5.2 • high molecular weight keratin and D240 were examined; the findings support the above diagnosis. |
|
| 82 yo f w/ hard 4 cm mass | Ndk6 | Ductal Carcinoma with abundant mucin production |
|
| 67 yo f w/ solid breast lesion | Ndk6 | Medullary Carcinoma Large anaplastic cells with giant nucleoli • numerous stripped malignant nuclei • scattered lymphocytes • and necrosis |
|
| 68 yo m w/ breast mass | Ndk6 | Ductal Carcinoma |
|
| 59 yo f w/ history of melanoma | Ndk6 | Consistent with metastatic melanoma |
|
| 25 yo f w/ unchanged breast nodule for years | Ndk6 | Fibroadenoma |
|
| 88 yo f w/ a 4.3 cm breast mass | Ndk6 | Poorly differentiated carcinoma Resection diagnosis: Metaplastic carcinoma • invasive • grade 3/3 with <50% ductal differentiation and 95% non-specific mesenchymal differentiation (polygonal • round • and spindle cells) |
|
| 48 yo F w/ seroma. R/o ALCL. | Ndk6 | Negative for malignancy- proteinaceous debris with small amount of admixed blood |
|
| 46 yo F w/ breast cyst | Ndk6 | No malignant cells identified- Abundant foamy histiocytes consistent with cyst contents |
|
| 60 yo M with left breast mass | Ndk6 | Consistent with fat necrosis |
|
| 86 yo F w/ right breast mass | Ndk6 | Adenocarcinoma with apocrine differentiation |
|
| 54 yo F 3 cm right axillary mass • history of metaplastic breast carcinoma excised 3 months ago | Ndk6 | metastatic carcinoma with squamous differentiation • c/w metaplastic carcinoma |
|
| 74 yo F history of right breast ca s/p mastectomy and radiation 14 years ago • now chest wall mass and erythema | Ndk6 | spindle cell sarcoma c/w angiosarcoma |
|
| 42 yo F right breast mass • history of retroperitoneal liposarcoma | Ndk6 | metastatic liposarcoma with myxoid and round cell features |
|
| 46 yo F thickening of left breast tissue at 12:00 | Ndk6 | Invasive ductal carcinoma with mucin |
|
| 19 yo F rubbery 2 cm right breast mass | Ndk6 | Fibroadenoma |
|
| 50 yo M right breast mass | Ndk6 | Consistent with ductal carcinoma |
