WSI21-128

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Subspecialty Cytology

Set Cytology

Topic Salivary Gland

Presenter MGH

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Toggle columns: Diagnosis

Case	Clinical history	Requester	Diagnosis
Case	Clinical history	Requester	Diagnosis
Case 1	53M	Em99	Mucoepidermoid carcinoma • low-grade
Case 2	40-year-old female. Left parotid mass.	Iac0	Bland-appearing spindle cells • consistent with nodular fasciitis. Molecular testing confirmed USP6-rearrangement.
Case 3	22yo M with 3.1cm left submandibular mass x 3 years	Mlz8	Cellular • myoepithelial-predominant pleomorphic adenoma
Case 5	72yo F with right parotid mass	Mlz8	Pleomorphic adenoma
Case 6	73-year-old female.	Iac0	Merkel cell carcinoma
Case 7	38-year-old female. Left temporal/supra-auricular mass.	Iac0	Adenoid cystic carcinoma.
Case 8	49-year-old male. Parotid mass.	Iac0	Pleomorphic adenoma • myoepithelial-rich
Case 9	59F. Left neck/mandible. History of ductal carcinoma of breast.	Iac0	Salivary duct carcinoma
Case 10	60F. Parotid mass.	Iac0	Atypical basaloid cells. Resection consistent with basal cell adenoma.
Case 11	69M. Parotid mass.	Iac0	Bland-appearing ductal cells with abundant chronic inflammation. Resection - low-grade mucoepidermoid carcinoma with CRTC1-MAML2
Case 12	59 y/old M right parotid mass stable for several years	Lcm51	Pleomorphic adenoma
Case 13	62 year old female with 1.1 x 1.4 x 1.8 cm left parotid tail mass.	Mc1192	Warthin tumor
Case 14	64 year old female with left parotid mass	Pab16	mucoepidermoid carcinoma
Case 15	55 year old man with a 2 year history of a parotid mass.	Cfh13	Benign: Cellular pleomorphic adenoma
Case 16	58M • left parotid mass	Mlz8	SALIVARY GLAND NEOPLASM OF UNCERTAIN MALIGNANT Potential (SUMP). Atypical matrix-producing neoplasm with prominent matrix globules • ddx adenoid cystic carcinoma • atypical PA • others
Case 17	73M. History of squamous cell carcinoma of temple.	Iac0	Metastatic poorly differentiated squamous cell carcinoma • with focal keratinization to parotid and neck lymph node.
Case 18	45 yo F with a history of a resected salivary gland malignancy. Now presenting with a 10 cm pelvic mass.	Cfh13	Metastatic adenoid cystic carcinoma.
Case 19	32F hx of Sjogren. Parotid and submandibular sialadenitis.	Iac0	Eosinophilic sialadenitis (query eosinophilic sialodochitis)
Case 20	1.7 cm well circumscribed hypoechoic mass in the parotid	Est105	Suspicious for malignancy • suspicious for acinic cell carcinoma
Case 21	62 yo F with a 4 year history of a growing parotid mass	Cfh13	SUMP. Basaloid neoplasm with atypia. No overt features of malignant transformation.
Case 22	70 yo M • smoker • with a right parotid mass	Est105	Warthin Tumor
Case 23	79 yo M never smoker • with a 1.2 cm parotid mass.	Cfh13	Non-Neoplastic. Abundant amylase crystalloids with scattered inflammatory cells.
Case 24	48 yo M with incidentally identified 2 cm parotid nodule.	Cfh13	Mucoepidermoid carcinoma.
Case 25	75M. Parotid mass.	Iac0	Warthin tumor.
Case 26	70M. Parotid mass.	Iac0	Warthin tumor.
Case 27	62F. Left parotid mass.	Iac0	SUMP - basaloid neoplasm. Fusion assay negative for rearrangement. Subsequent resection - Cellular • myoepithelial-rich pleomorphic adenoma with basaloid features
Case 28	88 YO • parotid mass	Td693	Oncocytic neoplasm favor oncocytoma
Case 29	67-year-old woman with 2.3 cm lesion within superficial lobe of parotid gland	Njc35	Neoplasm: Benign; Warthin Tumor
Case 30	58M. Parotid mass.	Iac0	Adenoid cystic carcinoma
Case 31	79 yo female	Dc679	Atypical cells and amylose crystals (likely benign)
Case 32	48 yo male	Dc679	Warthin tumor
Case 33	48 yo male	Dc679	A. INTRAPAROTID LYMPH NODE BX RIGHT: Warthin tumor (see comment). Comment: The small core biopsy shows columnar-lined oxyphilic epithelium with underlying lymphoid tissue composed predominantly of small lymphocytes with rare small reactive appearing germinal centers. Immunohistochemical stains show that the underlying lymphocytic infiltrate is composed of aggregates of CD20+ • CD5- B cells with intervening CD3+ CD5+ T cell rich regions. BCL2 stains most lymphocytes with a rare small germinal centers negative for BCL2. Flow cytometry is negative for a B cell lymphoproliferative disorder (see below). The findings support a diagnosis of Warthin tumor.
Case 34	60 yo male	Dc679	Secretory carcinoma
Case 139	69 yo f w/ history of carcinoma. S/p chemo and radiation with new cheek nodule.	Ndk6	Mucin-producing carcinoma morphologically consistent with involvement by the patient's known primary endocrine mucin-producing sweat gland carcinoma.
Case 140	70M. Left neck LN. History of mucoepidermoid carcinoma of hard palate.	Iac0	Metastatic high-grade mucoepidermoid carcinoma with CRTC1::MAML2 fusion.
Case 141	80M. Lesion of parotid gland.	Iac0	Benign. Amylase crystalloids and cyst contents.
Case 142	Secretary carcinoma	Sxm	Secretary carcinoma
Case 143	79 year old female with history of Merkel cell carcinoma involving the left submandibular gland. Now with right submandibular lesion up to 2.0cm.	Tz046	Metastatic neuroendocrine carcinoma • compatible with patient's known Merkel cell carcinoma.