| _creationDate | March 20, 2025 |
| _modificationDate | March 20, 2025 |
| _creator | Si787 |
| _fullText | {{ServiceRequestCase
|identifier=WSI21-134-Case-37
|intent=order
|code=study
|category=409073007
|subject=MGH
|requester=Ndk6
|performer=MGH
|orderDetail=case
|locationCode=learn
|access=Public
|status=completed
|origin=CPOE
|priority=routine
|basedOn=WSI21-134
|requisition=Cytology
|reasonCode=61 y ... |
| _numRevisions | 1 |
| _isRedirect | No |
| identifier | WSI21-134-Case-37 |
| basedOn | WSI21-134 |
| requisition | Cytology |
| intent | order |
| category | 409073007 |
| priority | routine |
| code | study |
| orderDetail | case |
| subject | MGH |
| occurrenceDateTime | December 31, 1969 7:00:00 AM |
| authoredOn | March 20, 2025 3:25:34 PM |
| requester | Ndk6 |
| performer | MGH |
| locationCode | learn |
| reasonCode | 61 yo M with HIV and new axillary and mediastinal LAD |
| supportingInfo | Positive for malignancy- HHV8-positive large cell lymphoma • consistent with primary effusion lymphoma
NOTE: The pleural fluid specimen consists of abundant large • atypical lymphoid cells with oval to irregular • convoluted nuclei • dispersed chromatin • and multiple small • prominent nucleoli with a moderate amount of brightly eosinophilic cytoplasm. Immunohistochemistry reveals that the large lymphoid cells stain positively for HHV8 and CD30. CD3 shows weak staining in rare large lymphoid cells and highlights a small population of admixed small • reactive T cells. CD20 and Pax-5 are negative. In-situ hybridization for EBV (EBER) is negative. Overall • the morphologic and immunohistochemical features are consistent with HHV8-related primary effusion lymphoma. An unusual feature is the absence of EBV as most primary effusion lymphomas are co-infected by HHV8 and EBV. |
| sequence | 37 |
| access | Public |
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| createdDateTime | March 20, 2025 3:25:34 PM |
| operator | Ndk6 |
| reasonCode | HHV-8 B3 |
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| createdDateTime | March 20, 2025 3:25:34 PM |
| operator | Ndk6 |
| reasonCode | PAX5 (APX) B5 |
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| view | hide |
| createdDateTime | March 20, 2025 3:25:34 PM |
| operator | Ndk6 |
| reasonCode | EBER B2 |
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| createdDateTime | March 20, 2025 3:25:34 PM |
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| view | hide |
| createdDateTime | March 20, 2025 3:25:34 PM |
| operator | Ndk6 |
| reasonCode | EBER RNA Control B2 |
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| createdDateTime | March 20, 2025 3:25:34 PM |
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| createdDateTime | March 20, 2025 3:25:34 PM |
| operator | Ndk6 |
| reasonCode | HE Surf Recut 2u |
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