WSI21-134: Pleural, Pericardial, and Peritoneal Fluids
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| Case | Clinical history | Requester | Diagnosis |
|---|---|---|---|
| Case | Clinical history | Requester | Diagnosis |
|
| 18-year-old male. History of glioblastoma. | Iac0 | Metastatic glioblastoma. |
|
| 80yo M with left-sided pleural effusion | Mlz8 | Metastatic small cell lung carcinoma |
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| 69yo F with pleural effusion | Mlz8 | Metastatic breast carcinoma (h/o invasive lobular carcinoma) |
|
| 48M • kidney failure. Pleura FNA. | Iac0 | Extramedullary hematopoiesis. |
|
| Over 90-year old male with significant asbestos exposure | Lcm51 | Mesothelioma |
|
| Pericardial effusion and history of parotid mass and atrial mass | Mlz8 | Metastatic Merkel cell carcinoma (from parotid primary) |
|
| 33F. Peritoneal carcinomatosis. | Iac0 | SMARCB1/INI1-deficient malignant epithelioid neoplasm. |
|
| 45 y/old F Long Hx of ESRD post kidney transplant. New effusion • duodenal mass and peritoneal nodules. | Lcm51 | PTLD • DLBCL type. |
|
| 41M. History of clear cell sarcoma of finger. | Iac0 | Metastatic clear cell sarcoma. |
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| 73y/old F with right pleural effusion and flank pain. | Aja51 | Dx Epithelioid mesothelioma |
|
| 60 y/old F with new pleural effusion and prior "soft tissue" tumor in the arm. | Aja51 | Metastatic epithelioid hemangioendothelioma |
|
| 79 yo male | Ndk6 | Multiple myeloma |
|
| 50 yo female with history of metastatic carcinoma with bilateral pleural effusions | Ndk6 | Metastatic ovarian carcinoma • clear cell type |
|
| 65 yo M with a history of myeloma. | Cfh13 | Positive. Recurrent multiple myeloma to pleura. |
|
| HISTORY OF MULTIPLE MYEOMA WITH PLASMACYTOMA. NOW HAS PLEURAL EFFUSIONS | Pab16 | Plasma cell myeloma |
|
| 78 YO male with h/o adenocarcinoma of pyloric antrum and ascites | Ndk6 | Metastatic adenocarcinoma c/w patient's known malignancy |
|
| Hx triple negative breast cancer | Est105 | Metastatic breast carcinoma |
|
| 18-year-old man | Eh441 | Burkitt lymphoma |
|
| 55 yo F with a remote history of breast carcinoma. | Cfh13 | Metastatic adenocarcinoma • consistent with breast primary. |
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| 55 yo M with chronic pleural effusion. | Cfh13 | Positive for malignant cells. Epithelioid hemangioendothelioma. |
|
| 52 yo F with acute respiratory failure in the setting of cocci and remote myeloma. | Cfh13 | Malignant cells present • consistent with involvement by the patient's known multiple myeloma. |
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| 68yo man with a history of oncocytic thyroid carcinoma (metastatic to one lymph node) and clear cell renal cell carcinoma | Ez278 | Metastatic oncocytic carcinoma • consistent with spread from thyroid primary. |
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| 68 yo woman with an ovarian mass | Cfh13 | Positive for metastatic ovarian serous carcinoma in a background of mucinous borderline tumor. |
|
| 73 yo man with ascites noted on surveillance following a Whipple for pancreatic carcinoma | Cfh13 | Malignant mesothelioma • epithelioid type. |
|
| 27 yo F with unrescetable thymic carcinoma | Ndk6 | Consistent with patient's known thymic carcinoma. Immunohistochemical studies show that the malignant cells are positive for p63 and CD5 • supporting the diagnosis. |
|
| 80-year-old man | Njc35 | Epithelioid mesothelioma.
Fibrosis and multinucleated giant cell reaction to polarizable foreign material • consistent with talc pleurodesis. Note: Immunohistochemistry - tumor cells are positive for calretinin and WT1. They show loss of membranous/ cytoplasmic expression of merlin/NF2. They show retained expression of MTAP. |
|
| 49M • ascites fluid | Mlz8 | Metastatic gastric signet ring cell adenocarcinoma |
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| 69F. Pleural based mass. | Iac0 | Epithelioid mesothelioma. |
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| 73 yo male | Dc679 | Metastatic Ewing Sarcoma |
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| 34 yo male with left empyema and c/f lymphoma | Ndk6 | High-grade B-cell lymphoma • consistent with Burkitt lymphoma |
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| 75 yo male | Ndk6 | Atypical lymphoid cells present • consistent with involvement by mantle cell lymphoma |
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| 72 yo female with thyroid cancer with recurrent right pleural effusion | Ndk6 | Metastatic carcinoma • consistent with the patient’s thyroid primary |
|
| 67F. Pelvic mass. Pelvic ascites. | Iac0 | Mucinous epithelium • consistent with involvement by ovarian mucinous neoplasm. Resection: borderline mucinous neoplasm. |
|
| 62F. History of papillary thyroid carcinoma. Now with pleural effusion. | Iac0 | Metastatic papillary thyroid carcinoma. |
|
| 20M. History of CNS lymphoma. | Iac0 | ALK-positive anaplastic large cell lymphoma (ALCL). |
