DZI20-194: OLI GYN

From MGH Learn Pathology


Request type Study
Subspecialty Gynecologic
Set Frozen Conference
Topic OLI GYN
Presenter Oliva, Esther,MD


Toggle columns: Diagnosis

Case Clinical history Requester Diagnosis
Case Clinical history Requester Diagnosis

Case 1


82 yo with 3.5 cm grey-white fibrotic mass extending from outer surface of ovary Mjf79 benign spindle cell proliferation c/w fibroma Permanent: Fibroma

Case 2


60 yo F with a 7.5 cm lobulated solid and cystic adnexal mass. Cystic component contains papillary excrescences Mjf79 High-grade serous carcinoma Permanent: High-grade serous carcinoma

Case 3


53 yo F with a 8.8 cm smooth walled unilocular cyst with no excrescences and filled with tenacious fluid Mjf79 mucinous cystadenoma

Case 4


40 yo F with 4.6 cm cystic mass. Outersurface grey-pink with shaggy cautery. Unilocular cyst filled with dark red-brown thick fluid Mjf79 endometriotic cyst

Case 5


41 yo F with adnexal mass. Gross: aggregate of polypoid soft tissue Mjf79 High-grade serous carcinoma with TCC like morphology Permanent: High-grade serous carcinoma with TCC like morphology (patient had BRCA mutation)

Case 6


53 yo F 9.3 cm disrupted adnexal cystic mass. Smooth thin wall unilocular focal excrescences straw colored fluid Mjf79 serous cystadenoma Permanent: serous papillary cystadenoma

Case 7


46 yo F with a 12.9 cm solid and cystic mass Mjf79 High-Grade carcinoma - ?clear cell Permanent: Clear cell carcinoma

Case 8


26 yo F with 13 cm ovarian mass. Cyst contents pasty yellow with hair. Cyst lining smooth. Mjf79 mature cystic teratoma

Case 9


4 yo F with 15 cm adnexal mass encapsulated rubbery mass. Friable fleshy cut surfaces solid and gray Mjf79 immature teratoma

Case 10


43 yo F 3.5 cm cystic ovary. Cyst has smooth lining no excresences Mjf79 benign functional cyst Permanent: Corpus luteum cyst

Case 11


63 yo F 18.5 cm white-purple adnexal mass with predominantly smooth surface with focal adhesions. Sectioning reveals cystic to solid and necrotic cut surfaces. Filled with tenacious fluid. Mjf79 mucinous cystadenocarcinoma Permanent: mucinous cystadenocarcinoma grade 1 arising in association with borderline tumor expansile invasion intestinal type

Case 12


63 yo with a 1.9 cm yellow gritty firm and ill-defined adnexal lesion Mjf79 Brenner tumor

Case 13


71 yo F with a 14 cm multiloculated mass filled with tenacious fluid. Lining shows multiple solid nodular areas. Mjf79 favor mucinous borderline tumor Permanent: Mucinous borderline tumor

Case 14


67 yo F with a 16.5 cm solid and cystic mass (solid area - lobulated with fibrous bands) Mjf79 endometrioid adenocarcinoma Permanent: adenometrioid adenocarcinoma grade 2/3 arising out of adenofibroma

Case 15


68 yo F 11.8 cm tan-yellow solid mass with areas of hemorrhage and necrosis Mjf79 poorly diff favor carcinosarcoma permanent: carcinosarcoma

Case 16


49 yo F 16.5 cm solid tan-white mass with prominent nodularity. Sections: solid multilobulated TW with fibrous bands and multifocal areas of softening and cystic change Mjf79 Favor stromal tumor ?granulosa cell tumor Permanent: Adult Granulosa Cell Tumor

Case 17


83 yo F with a 5.4 cm cystic mass with multiple tan-white firm thickened areas with associated papillary excrescences. Mjf79 serous cystadenofibroma

Case 18


41 yo F with a 15.5 cm cystic mass. Multiloculated cystic mass with a 9.5 cm area of friable papillary excresences with an adjacent indurated nodularity measuring 9 cm Mjf79 serous borderline

Case 19


61 yo F with a 3.1 cm polypoid endometrial mass Mjf79 adenocarcinoma grade 2 invasive with involvement of adenomyosis probably <50% Permanent: endometrial endometrioid adenocarcinoma grade 2/3 invasive of inner half 0.8mm in 18mm)

Case 20


71 yo F with a 7.2 cm tan-white friable fungating endometrial mass Mjf79 endometrial adenocarcinoma invasive to outer half Permanent: endometrial adenocarcinoma grade 1 invasive into outer half (28mm in 35mm)

Case 21


67 yo F with a 5.1 cm tan-white fungating endometrial mass and a 13 cm tan-white solid-cystic adnexal mass. Mjf79 FX1) uterus: adenocarcinoma close to 50% 2) Fibroma

Permanent 1: endometrioid adenocarcinoma grade 2 invasive 8mm in 24 mm conspicuous adenomyosis involvement

Permanent 2: Fibroma with cystic degeneration

Case 22


58 yo F with a 3.3 cm exophytic endometrial mass Mjf79 endometrial adenocarcinoma with sq diff >50% Permanent: Endometrioid adenocarcinoma grade 1 invasive into outer half with extensive MELF (18 into 24)

Case 23


55 yo F with a 2.2 cm friable endometrial mass Mjf79 endometrioid endometrial adenocarcinoma grade 1-2 no definitive invasion Permanent: endometrial endometrioid adenocarcinoma grade 2/3 confined to endometrium