GPR: 2019 - Week 14

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Clinical history

30 year old male with a crushed chest s/p MVA


GPR19-6 -Picture1.png


Registered users must be logged in to access the interactive quiz.


GPR19-6 -Picture1.png

 
Fat emboli
  • Seen after injury to bone or fibroadipose tissue
  • Also associated with CPR, burns, soft tissue injury, osteomyelitis, Diabetes, barotrauma, surgeries of fatty tissues, septicemia, acute pancreatitis, fatty liver of alcoholism, and steroid therapy
  • Petechial hemorrhages involving the white matter, not limited to the corpus callosum
 

GPR19-6 -Picture3.png

 

Gliding Contusion

  • Also associated with acceleration/deceleration injuries
  • Linear or oval hemorrhages within the white matter of the first frontal gyri, caused by anterior-posterior ‘gliding’ movements of the brain
 

GPR19-6 -Picture2.png

 

Diffuse axonal injury

  • Injury associated with acceleration/deceleration
  • Grossly may see petechial hemorrhages within corpus callosum and rostral midbrain
 

GPR19-6 -Picture4.png

 

Diffuse Petechial Hemorrhages Due to thrombotic thrombocytopenic purpura (TTP)

  • 70 year old patient with acute myeloid leukemia and associated TTP with thrombotic angiopathy
  • Diffuse, scattered petechial hemorrhages involving the gray matter
 
  • Dr. Hedley-Whyte
  • Dr. Martinez-Lage
  • Dr. Samore
  • Dr. Ordulu
  • Dr. Hedley-Whyte
  • Dr. Martinez-Lage
  • Dr. Samore
  • Dr. Ordulu
  • GPR Quiz

    Clinical history

    30 year old male with a crushed chest s/p MVA


    GPR19-6 -Picture1.png


    Registered users must be logged in to access the interactive quiz.

    Answer[edit]


    GPR19-6 -Picture1.png

     
    Fat emboli
    • Seen after injury to bone or fibroadipose tissue
    • Also associated with CPR, burns, soft tissue injury, osteomyelitis, Diabetes, barotrauma, surgeries of fatty tissues, septicemia, acute pancreatitis, fatty liver of alcoholism, and steroid therapy
    • Petechial hemorrhages involving the white matter, not limited to the corpus callosum
     

    DDx1[edit]


    GPR19-6 -Picture3.png

     

    Gliding Contusion

    • Also associated with acceleration/deceleration injuries
    • Linear or oval hemorrhages within the white matter of the first frontal gyri, caused by anterior-posterior ‘gliding’ movements of the brain
     

    DDx2[edit]


    GPR19-6 -Picture2.png

     

    Diffuse axonal injury

    • Injury associated with acceleration/deceleration
    • Grossly may see petechial hemorrhages within corpus callosum and rostral midbrain
     

    DDx3


    GPR19-6 -Picture4.png

     

    Diffuse Petechial Hemorrhages Due to thrombotic thrombocytopenic purpura (TTP)

    • 70 year old patient with acute myeloid leukemia and associated TTP with thrombotic angiopathy
    • Diffuse, scattered petechial hemorrhages involving the gray matter
     

    Acknowledgments

    • Dr. Hedley-Whyte
    • Dr. Martinez-Lage
    • Dr. Samore
    • Dr. Ordulu
  • Dr. Hedley-Whyte
  • Dr. Martinez-Lage
  • Dr. Samore
  • Dr. Ordulu

  • This week's Gross Pathology Roundup was presented by [[| , ]] on Mon, Apr 01, 2019.This week's Gross Pathology Roundup was presented by [[| , ]] on Mon, Apr 01, 2019.