WSI24-127-Case-3

From MGH Learn Pathology
WSI24-127-Case-3
A 40-year-old male never-smoker presented with a 1 year history of progressive dyspnea on exertion, and dry cough for six months, occasional wheezing and chronic fatigue. The patient is an engineer, working as project manager, but reported a history of exposure to engine exhaust, benzene and carbon black in the 90’s. His medical history included ocular migraines and intermittent “hives with stress”. Pulmonary function tests showed an FEV1/FVC of 48%, FEV1 29% and DLCO 44%. Alpha-1 antitrypsin levels were found normal several times. ANA and RF were negative. IgG levels were low, 595.
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June 22, 2025 3:00:00 PM