WSI22-117: Obstetrical didactic - Tuesday, August 20, 2024
From MGH Learn Pathology
Request details
- Request type AP didactic (PGY2+) - BWH
- Subspecialty Obstetrical
- Topic Gestational Trophoblastic Disease
- Presenter Quade, Bradley J.,MD, PhD
- Date and time Tuesday, August 20, 2024 12:00 PM
| Case | Clinical history | Requester |
|---|---|---|
| Case | Clinical history | Requester |
|
| 20 year-old patient delivered a singleton at 31 6/7 weeks. The baby had Apgars of 7 and 8 at 1 and 5 minutes • respectively. | Bq01 |
|
| 37 year-old patient with abnormally rising beta HCG. Gross shows a hemorrhagic mass. | Bq01 |
|
| Spontaneous abortion 5 months ago; now presents with 8 cm ovarian mass and HCG of 180 • 000. Gross shows a hemorrhagic mass. | Bq01 |
|
| 30 year-old with 12-week missed abortion 4 months prior to hysterectomy. Fetal and villous tissue noted on prior pathology specimens. Now presents with hemorrhagic mass and elevated HCG. | Bq01 |
|
| 41 year-old infertility patient had a missed abortion having multicystic placenta (by US) 5 months • retained POC 2 months ago • persistent HCG 1 month ago --> EMC for your review submitted by Troph Clinic during visit for 2nd opinion of the clinical dx of persistent GTD Hint: p57 is negative | Bq01 |
|
| 26 y.o. G1 P0. Ultrasound at 7 weeks showed fetal heart motion • but a second study at 10 weeks did not. | Bq01 |
|
| Same patient as previous case (Case 6) • but now has "Persistent Gestational Trophoblastic Disease" (plateau of post-evacuation beta HCG levels); offered chemo or 2nd curettage (elected the later). | Bq01 |
|
| 44 year-old presenting with heavy vaginal bleeding and passage of POC c/w SAB. | Bq01 |
|
| 46 year-old with anterior abdominal wall cyst. Last known pregnancy was > 10 yr ago. Diagnosed and treated for PSTT 3 yr ago. Now consulting BWH GYN oncology regarding recurrent PSTT. | Bq01 |
|
| Gestational trophoblastic neoplasia resistant to chemo | Bq01 |
