WSI21-53-Case-5

Sequence	Case	Clinical history	Diagnosis
1	WSI21-53-Case-1 WSI21-53-Case-1	60 year-old man with a heavy smoking history presented with a 3.7 cm right hilar mass causing occlusion of the RUL bronchus and RUL volume loss, severe narrowing of the right bronchus intermedius, a 2.1 cm RUL mass and other micronodular densities in the same lobe, as well as multistation mediastinal and right supraclavicular lymphadenopathy. 60 year-old man with a heavy smoking history presented with a 3.7 cm right hilar mass causing occlusion of the RUL bronchus and RUL volume loss, severe narrowing of the right bronchus intermedius, a 2.1 cm RUL mass and other micronodular densities in the same lobe, as well as multistation mediastinal and right supraclavicular lymphadenopathy.	Squamous cell carcinoma with a (minor) adenocarcinoma component Squamous cell carcinoma with a (minor) adenocarcinoma component
2	WSI21-53-Case-2 WSI21-53-Case-2	69 year-old man with a history of thyroid cancer presented with airway obstruction. Three slides from a 2019 biopsy and one slide from the trachea 69 year-old man with a history of thyroid cancer presented with airway obstruction. Three slides from a 2019 biopsy and one slide from the trachea	Papillary carcinoma (anaplastic) invading into the trachea Papillary carcinoma (anaplastic) invading into the trachea
3	WSI21-53-Case-3 WSI21-53-Case-3	73 year-old man with a 6.0 cm right lower lobe mass. What is the anatomical location of the mass? What it the diagnosis? 73 year-old man with a 6.0 cm right lower lobe mass. What is the anatomical location of the mass? What it the diagnosis?	Large cell carcinoma predominantly in the airway Large cell carcinoma predominantly in the airway
4	WSI21-53-Case-4 WSI21-53-Case-4	59 year-old woman with a never smoking history presented with a right upper lobe mass. 59 year-old woman with a never smoking history presented with a right upper lobe mass.	NSCLC with a pleomorphic features. Molecular testing found a MET exon 14 skipping mutation. NSCLC with a pleomorphic features. Molecular testing found a MET exon 14 skipping mutation.
5	WSI21-53-Case-5 WSI21-53-Case-5	72 year-old woman with a history of LLL segmentectomy for squamous cell carcinoma (1.8cm) now presented with a mass in RUL and mediastinal lymphadenopathy. 72 year-old woman with a history of LLL segmentectomy for squamous cell carcinoma (1.8cm) now presented with a mass in RUL and mediastinal lymphadenopathy.	SMARCA4 deficient thoracic malignancy SMARCA4 deficient thoracic malignancy

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