DZI20-210-Case-21
NA
SKIN, LEFT LATERAL THIGH, SHAVE BIOPSY, GAMMA DELTA T CELL LYMPHOMA.
IHC: atypical lymphocytes are negative for CD4 and CD8, expressing a gamma-delta T cell phenotype, positive for CD3 and CD7 with partial loss of CD5 expression. CD56 is negative; partial expression of TIA-1 and granzyme B is noted. BF1 (alpha/beta TCR) is negative. Numerous large cells are positive for CD30 (15%). In situ hybridization for EBV remained negative. Molecular analysis revealed a clonal rearrangement of the T cell gamma receptor.
December 31, 1969 7:00:00 PM
