DZI20-198: IAC BST

From MGH Learn Pathology


Request type Study
Subspecialty Bone and Soft Tissue
Set Frozen Conference
Topic IAC BST
Presenter Chebib, Ivan A.,MD


Toggle columns: Diagnosis

Case Clinical history Requester Diagnosis
Case Clinical history Requester Diagnosis

Case 1


Right axillary and chest wall masses in 61 yo F. Cores of tissue of axillary mass. Mjf79 Fibromatosis

Case 2


R hip r/o infection. 89 yo F Mjf79 Fibrin necrosis and acute and chronic inflammation. Up to 38 PMNs in 1 HPF Permanent: necrosis fibrin and fibrous tissue with acute and chronic inflammation and wear debris reaction

Case 3


right pelvis (65 yo F with h/o lung adenocarcinoma) Mjf79 FX1+Level) Metastatic carcinoma. Tissue scant requested additional tissue for permanents. FX2 2A) Bone and bone dust. FX3) Rare atypical cells Permanent: A) Poorly-differentiated metastatic adenocarcinoma. B) Bone dust and debris; no definitive carcinoma is identified. C) Metastatic poorly-differentiated adenocarcinoma.

Case 4


69 yo M interspinous ligament Mjf79 Pseudogout Permanent: Fibrous tissue and synovium with calcium pyrophsophate crystal deposits

Case 5


43 yo M with T10-T12 mass Mjf79 Chordoma Permanent: Chordoma conventional type

Case 6


8 yo M with posterior mediastinal mass Mjf79 mature ganglioneuroma Permanent: Neuroblastic tumor most consistent with ganglioneuroblastoma intermixed (Schwannian-stroma-rich). Frozen showed only ganglioneuroma

Case 7


24 yo F with 8th rib lesion Mjf79 fibrous dysplasia

Case 9


35 yo M T6 lesion Mjf79 Chondrosarcoma low-grade Permanent: Chondrosarcoma conventional (hyaline and myxoid subtype) grade 2/3

Case 10


61 yo F left distal ulnar bone tumor Mjf79 Enchondroma

Case 11


23 yo F left medial ankle mass Mjf79 tenosynovial giant cell tumor

Case 12


80 yo M L2 vertebral lesion Mjf79 bone marrow w/ atypical infiltrating cells and probable fibrosis. Await permanents. Permanent - metastatic poorly differentiated carcinoma most compatible with prostatic adenocarcinoma (based on IHC)

Case 13


42 yo F with right lower left soft tissue mass Mjf79 myxofibrosarcoma high-grade

Case 14


21 yo M with right proximal humerus lesion Mjf79 Osteochondroma

Case 15


55 yo M with distal humerus lesion Mjf79 FX1 (humerus marrow margin): Positive for malignancy FX2 (lesion): High-grade osteosarcoma Permanent: A) Positive for high-grade osteosarcoma. B) High-grade osteosarcoma (conventional - chondroblastic)

Case 16


9 yo F with buttock lesion Mjf79 Neurofibroma present at margin Permanent: Plexiform and diffuse neurofibroma

Case 17


33 yo M with popliteal fossa mass Mjf79 sarcoma Permanent: synovial sarcoma biphasic

Case 18


40 yo M with foot mass Mjf79 hemangioma

Case 19


54 yo F left posterior thigh mass Mjf79 Intramuscular myxoma

Case 20


53 yo F right axillary lesion Mjf79 Schwannoma

Case 21


32 yo F with R sciatic nerve mass Mjf79 MPNST Permanent: MPNST (patient was previously treated with radiation for MPNST of posterior thigh)