WSI24-411: Academic didactic - Thursday, December 11, 2025
From MGH Learn Pathology
Request details
- Request type AP didactic (409073007) - MGH
- Subspecialty Academic
- Set Grand Rounds
- Topic Grand Rounds
- Presenter Tashman, Joshua W.,MD, PhD
- Date and time Thursday, December 11, 2025 12:00 PM
| Case | Clinical history | Requester |
|---|---|---|
| Case | Clinical history | Requester |
|
| Man in his late 70s without relevant cancer history. He presents with a palpable testicular mass (~1.5-2 cm). Serum markers are negative and there is no evidence of extratesticular disease. A radical orchiectomy is performed. | Em99 |
|
| 2-month-old baby boy with a relatively large • sonographically complex testicular mass. Serum markers are negative. A radical orchiectomy is performed. | Em99 |
|
| 34-year-old man with small (~1.4 cm) self-discovered testicular painless tumor. Serum markers are unavailable. A radical orchiectomy was performed. | Em99 |
|
| 37 y.o. man with a history of testicular GCT containing teratoma • “somatic-type” RMS and ENET s/p orchiectomy + RPLND. Developed post-orchiectomy/RPLND recurrence treated with Etoposide + cisplatin + ifosfamide followed by Copanlesib (tumor showed a pathogenic PIK3CA variant). A complex multiorgan resection is performed to excise a large residual retroperitoneal mass. | Em99 |
|
| 46-year-old man presenting with left testicular mixed germ cell tumor • liver and lung metastases • and retrperitoneal/pelvic masses encasing the left ureter. Status post VIP • salvage TIP • and high dose intensified chemotherapy. Residual retroperitoneal and pelvic masses are resected. A section of the pelvic mass is provided. | Em99 |
|
| 26 year old patient with a paratesticular tumor involving epididymis. A resection of the lesion was performed at the time of bilateral vasectomy. | Em99 |
|
| Elderly man with a complex clinical history. He has a diagnosis of pulmonary sarcoidosis treated with prednisone and multiple episodes of pneumonia (after initiation of steroids). He now presents with a palpable testicular mass concerning for malignancy. | Em99 |
|
| Middle aged man with a remote history of a testicular tumor (> 5 years prior). Now presenting with retroperitoneal lymphadenopathy. A retroperitoneal lymph node dissection was performed. | Em99 |
|
| 5-year-old girl with Swyer syndrome undergoing bilateral gonadectomy. One of the gonads is shown. | Em99 |
|
| 11-year-old girl undergoing bilateral excisional biopsies of intraabdominal gonads. | Em99 |
|
| 60-year-old patient with a 5 cm in the right testicle. AFP is 4 ug/L. | Em99 |
