WSI24-293: Neuropathology didactic - Friday, May 2, 2025

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Request type AP didactic (409073007) - MGH
Subspecialty Neuropathology
Set [[]]
Topic Gliomas
Presenter Mount, Christopher W.,MD, PhD
Date and time Friday, May 2, 2025 1:00 PM



Case Clinical history Requester
Case Clinical history Requester

Case 1


56 year old man with an enhancing mass in the right frontal lobe Cx395

Case 2


26 year old man with an expansile non-enhancing mass in the left frontal cortex Cx395

Case 3


32 year old woman with a non-enhancing right frontal lesion. MR Spectroscopy suggests elevated 2-hydroxyglutarate in the lesion. Cx395

Case 4


15 year old boy with a cystic cerebellar lesion with an enhancing nodule. What molecular alteration might you expect to find by sequencing? Cx395

Case 5


9 year old boy with an expansile lesion of the pons infiltrating adjacent structures including the cerebellum. Cx395

Case 6


42 year old woman with a circumscribed nodular lesion along the 4th ventricle. Cx395

Case 7


18 year old man with an enhancing partially cystic lesion arising from the 4th ventricle. What is the significance of H3K27me3 staining in this setting? Cx395

Case 8


50 year old man with an intradural extramedullary enhancing lesion along the filum terminale Cx395