DZI20-239-Case-1

Sequence	Case	Clinical history	Diagnosis
1	DZI20-239-Case-1 DZI20-239-Case-1	65 yo woman with fatigue and abnormal CBC and smear. WBC 9.21; HGB 8.7 (L); HCT 24.6 (L) PLT 49 (L) MCV 103.4 (H) DIFF: NEUTS 19.1 (L); LYMPHS 36.5; REACTIVE LYMPHS 7.0 (H); MONOS 28.7 (H) (4 - 11 %); OTHER CELLS 8.7 (H) 65 yo woman with fatigue and abnormal CBC and smear. WBC 9.21; HGB 8.7 (L); HCT 24.6 (L) PLT 49 (L) MCV 103.4 (H) DIFF: NEUTS 19.1 (L); LYMPHS 36.5; REACTIVE LYMPHS 7.0 (H); MONOS 28.7 (H) (4 - 11 %); OTHER CELLS 8.7 (H)	Recurrent CMML2 vs AMML vs MDS EB2 Recurrent CMML2 vs AMML vs MDS EB2
2	DZI20-239-Case-2 DZI20-239-Case-2	68 yo man presenting to the ED with acute chest pain c/f aortic dissection noted to have an abnormal CBC and smear WBC 21.02; HGB 7.3; HCT 22.7; PLT 138; MCV 96. DIFF: Neutr 64; Lymph 12; Monos 1; Basos 1; Bands 1; Metas 2; Myelos 16; Other WBCs 3. 68 yo man presenting to the ED with acute chest pain c/f aortic dissection noted to have an abnormal CBC and smear WBC 21.02; HGB 7.3; HCT 22.7; PLT 138; MCV 96. DIFF: Neutr 64; Lymph 12; Monos 1; Basos 1; Bands 1; Metas 2; Myelos 16; Other WBCs 3.	One year reported history of ET never confirmed by bone marrow review on hydroxyurea. The current findings are suggestive of either progression of the disease or question the original diagnosis. If this was the diagnostic specimen MDS/MPN overlap would be a consideration. One year reported history of ET never confirmed by bone marrow review on hydroxyurea. The current findings are suggestive of either progression of the disease or question the original diagnosis. If this was the diagnostic specimen MDS/MPN overlap would be a consideration.
3	DZI20-239-Case-3 DZI20-239-Case-3	55 yo man with symptomatic lymphadenopathy, fatigue, sweats and an abnormal CBC and smear. WBC: 19.7 (H); HGB: 13.1 (L); HCT 39.3 (L); MCV: 89.9; PLT: 145 (L) Diff: Neutr 18.4; Lymph 57.8; Monos 4.4; Eos 0.9; Basos 0.9; Metas 0.9; Myelos 0.9; Other WBC 15% 55 yo man with symptomatic lymphadenopathy, fatigue, sweats and an abnormal CBC and smear. WBC: 19.7 (H); HGB: 13.1 (L); HCT 39.3 (L); MCV: 89.9; PLT: 145 (L) Diff: Neutr 18.4; Lymph 57.8; Monos 4.4; Eos 0.9; Basos 0.9; Metas 0.9; Myelos 0.9; Other WBC 15%	CLL with 5-7% prolymphocytes CLL with 5-7% prolymphocytes
4	DZI20-239-Case-4 DZI20-239-Case-4	58 yo woman presenting to the ED frail, with pain, nausea and fatigue. She is noted to have an abnormal CBC and smear. WBC:3.6 (L); HGB: 8.6 (L); HCT: 26.9 (L); MCV: 89.7; PLT: 27 (L) Diff: Neut: 40; Lymph 32; Monos 5; Eos 1; Bands 4; Atypical lymphs 2; Metas: 2; Myelos 3; Promyelos 1; Other WBCs: 10. 58 yo woman presenting to the ED frail, with pain, nausea and fatigue. She is noted to have an abnormal CBC and smear. WBC:3.6 (L); HGB: 8.6 (L); HCT: 26.9 (L); MCV: 89.7; PLT: 27 (L) Diff: Neut: 40; Lymph 32; Monos 5; Eos 1; Bands 4; Atypical lymphs 2; Metas: 2; Myelos 3; Promyelos 1; Other WBCs: 10.	IgA multiple myeloma with Rouleaux formation and circulating plasma cells. IgA multiple myeloma with Rouleaux formation and circulating plasma cells.

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