DZI19-121-Case-10
From MGH Learn Pathology
PLEOMOPHIC XANTHOASTROCYTOMA, BRAF V600E MUTANT
Histological diagnosis: Pleomorphic xanthoastrocytoma
WHO histological grade: II
Molecular information: BRAF V600E: MUTANT (sequencing) IDH: wildtype (IDH1/2 sequencing) P53: weak in rare tumor cells (immunohistochemistry, consistent with wildtype)
ATRX: nuclear expression retained (immunohistochemistry, consistent with wildtype)