DZI19-121-Case-10

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DZI19-121-Case-10
(ASCP CASE 9) 35 year old woman presents with new onset of tonic-clonic seizures
Integrated diagnosis:

PLEOMOPHIC XANTHOASTROCYTOMA, BRAF V600E MUTANT

Histological diagnosis: Pleomorphic xanthoastrocytoma

WHO histological grade: II

Molecular information: BRAF V600E: MUTANT (sequencing) IDH: wildtype (IDH1/2 sequencing) P53: weak in rare tumor cells (immunohistochemistry, consistent with wildtype)

ATRX: nuclear expression retained (immunohistochemistry, consistent with wildtype)
December 31, 1969 7:00:00 PM