WSI24-104: Sinus
From MGH Learn Pathology
Request details
- Request type Study
- Subspecialty Head and Neck
- Set [[]]
- Topic Sinus
- Presenter Faquin, William C.,MD, PhD
- Date and time Thursday, May 9, 2024 1:53 PM
Toggle columns: Diagnosis
| Case | Clinical history | Requester | Diagnosis |
|---|---|---|---|
| Case | Clinical history | Requester | Diagnosis |
|
| 61 year old male with sinus tumor. | Emw8 | Schwannoma. |
|
| 65 year old male with left maxillary sinus mass. | Emw8 | Oncocytic sinonasal papilloma. |
|
| 25 year old male with frontal sinus tumor. | Emw8 | c/w RCC-like sinonasal adenocarcinoma. |
|
| 82 year old female with nasal cavity mass. | Emw8 | Rosai Dorfman disease. |
|
| 78 year old female with nasal mass • epiphora and history of myxofibrosarcoma. | Emw8 | Malignant melanoma (+ for S-100 • HMB-45 • Sox-10). |
|
| 52 year old Haitian male. | Emw8 | HTLVI-associated adult T-cell lymphoma. (CD4+ • CD7- • CD25+ • EBER-) |
|
| 46 year old male with left nasal mass. | Emw8 | Chondrosarcoma grade 2-3/3. |
|
| 70 year old female with nasal cavity mass. | Emw8 | Pyogenic granuloma. |
|
| 37 year old female with nasal obstruction. | Emw8 | NK/T cell lymphoma (EBER+ • CD3+). |
|
| 49 year old female with left nasal mass. | Emw8 | Sinonasal meningioma. |
|
| 87 year old male with nasal skin lesion. | Emw8 | Angiosarcoma. |
|
| 55 year old male with history of leprosy and sinusitis. | Emw8 | Non-necrotizing granulomas c/w known leprosy. |
|
| 45 year old male with sinus and supraglottic mass. | Emw8 | Rosai-Dorfman Disease. |
|
| 10 year old male with right nasal mass. | Emw8 | Olfactory neuroblastoma. |
|
| 67 year old male with left maxillary cancer. | Emw8 | NUT carcinoma |
|
| 58 year old female with left nasal mass. | Emw8 | Biphenotypic sinonasal sarcoma; S100 • SMA + |
|
| 46 year old female with sinus mass. | Emw8 | Malignant melanoma. |
|
| 82 year old female with right maxillary sinus mass. | Emw8 | Sinonasal papilloma • oncocytic type. |
|
| 56 year old female with maxillary sinus polyps. | Emw8 | Sinonasal papilloma • inverted type with squamous features. |
|
| 71 year old female with nasal mass. | Emw8 | Biphenotypic sinonasal sarcoma. |
|
| 32 year old female with nasal mass. | Emw8 | Olfactory neuroblastoma • Hyams grade 3. |
|
| 37 year old female with maxillary sinus tumor. | Emw8 | Sinonasal teratocarcinosarcoma. |
|
| 49 year old male with right pyriform sinus mass. | Emw8 | Dedifferentiated liposarcoma. FISH + for MDM2 |
|
| 45 year old male with large nasal mass. | Emw8 | Plasmacytoma. |
|
| 50 year old female with sinonasal mass. | Emw8 | Sinonasal carcinoma with squamous and glandular features with inverted papilloma. |
|
| 78 year old female with sphenoid sinus mass. | Emw8 | Meningioma • WHO grade 1. |
|
| 1 year old female with large sinonasal mass. | Emw8 | Desmoid fibromatosis. |
|
| 65 year old male with right sinus mass. | Emw8 | Poorly differentiated neuroendocrine carcinoma. |
|
| 60 year old female with 1.5 cm nasal lesion. | Emw8 | c/w eosinophilic angiocentric fibrosis (IgG4 RD). |
|
| 76 year old female with sinonasal mass. | Emw8 | Ameloblastic carcinoma. |
|
| 43 year old female with maxillary cyst. | Emw8 | Calcifying odontogenic cyst. |
|
| 38 year old female with sinonasal mass. | Emw8 | Biphasic sinonasal neoplasm • most c/w olfactory neuroblastoma with divergent low-grade epithelial differentiation. |
|
| 49 year old male with sinus tumor involving ethmoid and left orbit. | Emw8 | Biphenotypic sinonasal sarcoma. IHC: S-100+ • SMA+ |
|
| 30 year old male with sinusitis. | Emw8 | Abundant allergic mucin. |
|
| 62 year old female sinus content. | Emw8 | Infiltrating meningioma. |
|
| 79 year old male with nasal mass • obstructing breathing. | Emw8 | Ameloblastoma (although w/incr mitoses) |
|
| 48 year old woman with 3 cm nasal mass which extends to the posterior choana and nasopharyx. | Emw8 | Biphenotypic sinonasal sarcoma.
S100 protein: positive • diffuse SMA: positive • patchy Desmin: positive • focal CD34: negative STAT6: negative Sox 10 negative AE1/3: negative Nuclear b-catenin: positive • focal Pan-TRK: positive • focal FISH shows pAX3 gene translocation |
|
| 37 year old female with maxillary sinus tumor. | Emw8 | Sinonasal teratocarcinosarcoma. |
|
| Posterior nasal mass in a 52 year old female. | Emw8 | Sinonasal hamartoma with osseous and serosanguinous features. |
|
| 63 year old female with sinonasal mass. | Emw8 | Sinonasal non-keratinizing SCC. |
|
| 63 year old female with sinonasal mass. | Emw8 | Sinonasal non-keratinizing SCC. |
|
| 63 year old female with sinonasal mass. | Emw8 | Sinonasal non-keratinizing SCC. |
|
| 63 year old female with sinonasal mass. | Emw8 | Sinonasal non-keratinizing SCC. |
|
| 42 year old male with sinonasal mass and lung mass. | Emw8 | Sinonasal teratocarcinosarcoma with lung met. |
|
| 63 year old female with sinonasal mass. | Emw8 | Sinonasal non-keratinizing SCC. |
|
| 42 year old male with sinonasal mass and lung mass. | Emw8 | Sinonasal teratocarcinosarcoma with lung met. |
|
| 63 year old female with sinonasal mass. | Emw8 | Sinonasal non-keratinizing SCC. |
|
| 63 year old female with sinonasal mass. | Emw8 | Sinonasal non-keratinizing SCC. |
|
| 63 year old female with sinonasal mass. | Emw8 | Sinonasal non-keratinizing SCC. |
|
| 63 year old female with sinonasal mass. | Emw8 | Sinonasal non-keratinizing SCC. |
|
| 42 year old male with sinonasal mass and lung mass. | Emw8 | Sinonasal teratocarcinosarcoma with lung met. |
|
| 60 year old male with history of sinonasal SCC. Now with recurrence. | Emw8 | High-grade transformation to SNUC. |
|
| 37 year old female with left nasal mass. | Emw8 | Pyogenic granuloma. |
|
| 69 year old male with large sinonasal and skull base mass. | Emw8 | c/w SNUC. |
|
| 54 year old female with 2.0 cm sinonasal mass. | Emw8 | Sinonasal glomangiopericytoma. |
|
| 79 year old female with sinus lesion. | Emw8 | Oncocytic sinonasal papilloma. |
|
| 57 year old female with nasal vault lesion. | Emw8 | Sinonasal non-keratinizing SCC. The tumor is + for HPV16. |
|
| 35 year old male with nasal cavity mass. | Emw8 | Olfactory neuroblastoma with olfactory carcinoma. |
|
| 62 year old male with sinus cyst. | Emw8 | Focal ameloblastoma. |
|
| 29 year old female with sinusitis. | Emw8 | Low-grade papillary adenocarcinoma. |
|
| 57 year old male with left nasal mass. | Emw8 | Low-grade non-intestinal sinonasal adenocarcinoma. |
|
| 70 year old female with pansinusitis. | Emw8 | Olfactory neuroblastoma. Hyams grade 2 of 4. |
|
| 37 year old male with tongue lesion. | Emw8 | Syphilis. |
|
| 51 year old male with post superior nasal mass. | Emw8 | Olfactory carcinoma. |
|
| 61 year old female with sinonasal mass. | Emw8 | c/w olfactory carcinoma. |
|
| 68 year old female with nasal mass. | Emw8 | Alveolar rhabdomyosarcoma. PAX3:DOX 01 fusion + Mycetoma. |
|
| 49 year old female with large sinonasal mass. | Emw8 | c/w SNUC |
|
| 61 year old male with nasopharynx mass. | Emw8 | DLBCL |
|
| 54 year old male with sinus mass. | Emw8 | Meningioma |
|
| 71 year old female with 2 cm maxillary sinus mass. | Emw8 | Respiratory epithelial adenomatoid hamartoma. |
|
| 74 year old female with left olfactory cleft (nasal) lesion. | Emw8 | REAH |
