WSI23-45: Urethra

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Request type Study
Subspecialty Genitourinary
Set Genitourinary
Topic Urethra
Presenter Sadow, Peter M.,MD, PhD
Date and time Saturday, April 1, 2023 12:00 PM


Toggle columns: Diagnosis

Case Clinical history Requester Diagnosis
Case Clinical history Requester Diagnosis

Case 1


67 year old male with small papillary tumors in penile urethra s/p TURP for bladder outlet obstruction Si787 Squamous papilloma with reactive atypia

Case 2


28 year old female with vaginal mass Si787 Pigmented PEComa. + HMB45 +Melan A +Des. - S100 -SMA

Case 3


45 year old male with history of seminoma 12 years prior as well as phosphaturic mesenchymal tumor of the femur now presents with a right retroperitoneal mass Si787 Anastomosing hemangioma (2.9 cm) of the genitourinary system

Case 4


55 year old female with h/o carcinosarcoma of the uterus now with pelvic clot versus tumor Si787 High grade malignant epithelioid neoplasm c/w involvement by the patient's known carcinosarcoma. Focal p53+. Focal CK7+

Case 5


71 year old male with 9.5 cm right posterior chest wall mass. Also with 10 cm mediastinum mass Si787 Eosinophilic and clear cell malignant neoplasm with focal papillary architecture c/w metastatic renal cell carcinoma clear cell type. + CD10 + PAX8 + RCC

Case 6


59 year old male s/p inguinal hernia repair. Noticed left groin mass. By PET enlarged bulky hypermetabolic nodes it the left external iliac distribution. No hx of cutaneous lesions or other carcinoma. Si787 Non-kertinizing HPV-related squamous cell carcinoma with comedo-type necrosis metastatic to a lymph node (7.0 cm) with other positive nodes. Primary differential is genital vs oropharyngeal

Case 7


30 year old male with an enlarging left epididymal mass Si787 Papillary cyst adenoma with clear cell features. PAX8+ RCC-.

Case 8


67 year old male with small papillary tumors in penile urethra s/p TURP for bladder outlet obstruction. Emw8 Squamous papilloma with reactive atypia.

Case 9


19 year old male with left testicular mass. Emw8 Malignant mixed germ cell tumor 10.1 cm.

80% yolk sac tumor. 20% teratoma. + LVI

pT2 NX M16

Case 11


18 year old hockey player with abdominal discomfort and CT scan to r/o colitis found to have 9 mm right-sided testis mass. Emw8 Epithelioid hemangioma (0.9 cm).

Case 12


45 year old male with history of seminoma 12 years prior as well as phosphaturic mesenchymal tumor of the right femur now presents with a right retroperitoneal mass. Emw8 Anastomosing hemangioma (2.8 cm) of the genitourinary system.

Case 13


55 year old female with h/o carcinosarcoma of the uterus now with pelvic clot versus tumor. Emw8 High grade malignant epithelioid neoplasm c/w involvement by the patient's known carcinosarcoma. Focal p53+ Focal CK7+

Case 14


71 year old male with 9.5 cm right posterior chest wall mass. Also with10 cm mediastinum mass. Emw8 Eosinophilic and clear cell malignant neoplasm with focal papillary architecture c/w metastatic renal cell carcinoma clear cell type.

+ CD10 + PAX8

+ RCC

Case 15


59 year old male s/p B inguinal hernia repair. Noticed L groin mass. By PET enlarged bulky hypermetabolic nodes in the L external iliac distribution. No history of cutaneous lesion or other carcinoma. Emw8 Non-keratinizing HPV-related squamous cell carcinoma with comedo-type necrosis metastatic to a lymph node (7.0 cm) with other positive nodes. Primary differential is genital vs oropharyngeal.

Case 16


30 year old male with von Hippel Lindau syndrome and a left epididymal mass. Emw8 Papillary cyst adenoma with clear cell features.

PAX8 +

RCC -

Case 17


28 year old female with vaginal mass. Emw8 Pigmented PEComa

+ HMB45 Melan A Des

- S100 SMA