WSI23-45: Urethra
From MGH Learn Pathology
Request details
- Request type Study
- Subspecialty Genitourinary
- Set Genitourinary
- Topic Urethra
- Presenter Sadow, Peter M.,MD, PhD
- Date and time Saturday, April 1, 2023 12:00 PM
Toggle columns: Diagnosis
Case | Clinical history | Requester | Diagnosis |
---|---|---|---|
Case | Clinical history | Requester | Diagnosis |
| 67 year old male with small papillary tumors in penile urethra s/p TURP for bladder outlet obstruction | Si787 | Squamous papilloma with reactive atypia |
| 28 year old female with vaginal mass | Si787 | Pigmented PEComa. + HMB45 • +Melan A • +Des. - S100 • -SMA |
| 45 year old male with history of seminoma 12 years prior as well as phosphaturic mesenchymal tumor of the femur now presents with a right retroperitoneal mass | Si787 | Anastomosing hemangioma (2.9 cm) of the genitourinary system |
| 55 year old female with h/o carcinosarcoma of the uterus • now with pelvic clot versus tumor | Si787 | High grade malignant epithelioid neoplasm c/w involvement by the patient's known carcinosarcoma. Focal p53+. Focal CK7+ |
| 71 year old male with 9.5 cm right posterior chest wall mass. Also with 10 cm mediastinum mass | Si787 | Eosinophilic and clear cell malignant neoplasm with focal papillary architecture c/w metastatic renal cell carcinoma • clear cell type. + CD10 • + PAX8 • + RCC |
| 59 year old male s/p inguinal hernia repair. Noticed left groin mass. By PET • enlarged • bulky • hypermetabolic nodes it the left external iliac distribution. No hx of cutaneous lesions or other carcinoma. | Si787 | Non-kertinizing HPV-related squamous cell carcinoma with comedo-type necrosis metastatic to a lymph node (7.0 cm) with other positive nodes. Primary differential is genital vs oropharyngeal |
| 30 year old male with an enlarging left epididymal mass | Si787 | Papillary cyst adenoma with clear cell features. PAX8+ • RCC-. |
| 67 year old male with small papillary tumors in penile urethra s/p TURP for bladder outlet obstruction. | Emw8 | Squamous papilloma with reactive atypia. |
| 19 year old male with left testicular mass. | Emw8 | Malignant mixed germ cell tumor 10.1 cm.
80% yolk sac tumor. 20% teratoma. + LVI pT2 NX M16 |
| 18 year old hockey player with abdominal discomfort and CT scan to r/o colitis found to have 9 mm right-sided testis mass. | Emw8 | Epithelioid hemangioma (0.9 cm). |
| 45 year old male with history of seminoma 12 years prior as well as phosphaturic mesenchymal tumor of the right femur now presents with a right retroperitoneal mass. | Emw8 | Anastomosing hemangioma (2.8 cm) of the genitourinary system. |
| 55 year old female with h/o carcinosarcoma of the uterus • now with pelvic clot versus tumor. | Emw8 | High grade malignant epithelioid neoplasm c/w involvement by the patient's known carcinosarcoma. Focal p53+ Focal CK7+ |
| 71 year old male with 9.5 cm right posterior chest wall mass. Also with10 cm mediastinum mass. | Emw8 | Eosinophilic and clear cell malignant neoplasm with focal papillary architecture c/w metastatic renal cell carcinoma • clear cell type.
+ CD10 + PAX8 + RCC |
| 59 year old male s/p B inguinal hernia repair. Noticed L groin mass. By PET • enlarged • bulky • hypermetabolic nodes in the L external iliac distribution. No history of cutaneous lesion or other carcinoma. | Emw8 | Non-keratinizing HPV-related squamous cell carcinoma with comedo-type necrosis metastatic to a lymph node (7.0 cm) with other positive nodes. Primary differential is genital vs oropharyngeal. |
| 30 year old male with von Hippel Lindau syndrome and a left epididymal mass. | Emw8 | Papillary cyst adenoma with clear cell features.
PAX8 + RCC - |
| 28 year old female with vaginal mass. | Emw8 | Pigmented PEComa
+ HMB45 • Melan A • Des - S100 • SMA |