WSI22-23: GI
From MGH Learn Pathology
Request details
- Request type Study
- Subspecialty Gastrointestinal
- Topic GI
- Presenter Mino-Kenudson, Mari,M.D.
- Date and time Wednesday, October 19, 2022 1:00 PM
Toggle columns: Diagnosis
| Case | Clinical history | Requester | Diagnosis |
|---|---|---|---|
| Case | Clinical history | Requester | Diagnosis |
|
| A 70-year-old woman with pseudogout underwent upper GI endoscopy for iron deficiency anemia and was found to have patchy plaques 2-4 cm in length and 2 cm across in the gastric antrum that did not scrape off. | Kx601 | Doxycycline-induced gastric mucosal injury |
|
| A 64-year-old man presented with melena. Upper GI endoscopy showed an ulcerated mass-like lesion in the antrum. | Mm768 | Iron pill gastritis |
|
| A 34-year-old woman with end stage kidney disease on dialysis presented with refractory nausea and vomiting and was found to have patchy moderate inflammation with edema • erythema • and granularity in the gastric body. | Mm768 | Lanthanum deposition |
|
| A 52-year-old man with metastatic intrahepatic cholangiocarcinoma presented with abdominal pain • nausea • vomiting and poor oral intake • and upper GI endoscopy found gastric ulcer in the prepyloric region and nodular mucosa in the pylorus of the stomach. | Mm768 | Selective internal radiation (SIR)-microspore induced gastritis |
|
| A 30-year-old woman with generalized abdominal distress/pain and dyspepsia; r/o celiac disease | Mm768 | Duodenal mucosa with normal villous architecture and increased intraepithelial lymphocytes secondary to NSAIDs use |
|
| A 66-year-old woman with a history of gout presented with chronic cough • vomiting and weight loss. | Mm768 | Colchicine toxicity |
|
| A 70-year-old woman with hypertension presented with chronic diarrhea and weight loss. Endoscopic examination showed mild mucosal nodularity in the small intestine. | Mm768 | Olmesartan enteropathy |
|
| A 70-year-old woman with cutaneous T cell lymphoma s/p bone marrow transplant (BMT) presented with diarrhea. | Mm768 | Graft-versus-host disease (GVHD) |
|
| A 46-year-old woman with a history of Loeys-Dietz syndrome and post cardiac transplant presented with diarrhea • abdominal pain and poor oral intake. | Mm768 | Mycophenolate mofetil (MMF)-associated colonic injury (mycophenolate injury) |
|
| A 65-year-old man with chronic lymphocytic leukemia presented with moderately severe • continuous • non-bloody diarrhea not responding to antimotility agents. | Mm768 | Idelalisib-associated enterocolitis |
|
| A 70-yea-old man with stage IV malignant melanoma on ipilimumab presented with diarrhea. | Mm768 | Ipilimumab-associated colitis |
|
| A 70-year-old woman with stage IV melanoma on nivolumab after progression on ipilimumab | Mm768 | Nivolumab-associated colitis • collagenous colitis pattern |
|
| A 52-year-old man with metastatic squamous cell carcinoma of the tongue presented with several episodes of diarrhea per day. A: random colon • B: rectum | Mm768 | Pembrolizumab-associated colitis • chronic active colitis pattern |
|
| A 55-year-old man with Melanoma on anti-PD-1/CTLA-4 combination developed diarrhea and abdominal pain. Clinical work-up showed an elevated tTG IgA titer (121 IU/mL). | Mm768 | Immune checkpoint inhibitor (ICI)-associated duodenitis |
|
| A 67-year-old man with a suspected mass in rectum seen on MRI | Mm768 | Lifting agent granuloma |
|
| A 91-year-old woman with perforated diverticulitis and abscess formation | Mm768 | Cholestipol deposition in the background of diverticular disease |
|
| A 73-year-old woman with chronic diarrhea r/o microscopic colitis | Mm768 | Systemic mastocytosis involving the colon |
|
| A 57-year-old woman with a white spot found in the left colon during screening colonoscopy | Mm768 | Strongyloides |
|
| A 67-year-old woman presented with left sided abdominal pain radiating to the left chest for a week and was found to have a 2.5 cm mass lesion in the pancreatic body with upstream pancreatic ductal dilatation. | Mm768 | Acinar cell carcinoma of the pancreas |
|
| A 79-year-old man presented with back pain. Work-up showed markedly heterogeneous appearance of the liver • which appears to be replaced by numerous hypodense masses • and a heterogeneous mass in the neck of the pancreas depicted by CT scan. | Mm768 | Mixed acinar-neuroendocrine carcinoma |
|
| A 38-year-old woman with an incidentally discovered • 4 cm mass in the pancreas | Mm768 | Pancreatoblastoma |
|
| A 11-year-old woman with a 5 cm heterogenous mass incidentally discovered after complicated appendicitis | Mm768 | Solid pseudopapillary neoplasm (SPN) of the pancreas |
|
| A 82-year-old man with history of recurrent pancreatitis presented with symptoms of acute pancreatitis and was found to have a cystic mass with the main pancreatic duct dilatation in the pancreatic head during work-up. | Mm768 | Intraductal papillary mucinous neoplasm (IPMN) • intestinal type |
|
| A 71-year-old man with an incidentally discovered • 6.7 x 2.7 cm multi-cystic mass in the head of the pancreas | Mm768 | Intraductal papillary mucinous neoplasm (IPMN) • pancreatobiliary type |
|
| A 70-year-old man with a multicystic mass with regions of mural soft tissue nodularity throughout the pancreas | Mm768 | Intraductal papillary mucinous neoplasm (IPMN) • oncocytic type / Intraductal papillary oncocytic neoplasm (IPON) |
|
| A 70-year-old man developed oily stools and was found to have pancreatic insufficiency several months ago. Further work-up identified a 4.0 cm segment of very irregular pancreatic duct with filling defects consistent with intraductal papillary tumors and/or mucous and a prominently dilated pancreatic duct to near 1.0 cm in the diameter in the body and tail of the pancreas without evidence of irregularity there. | Mm768 | Intraductal tubulopapillary neoplasm (ITPN) |
|
| A 71-year-old woman with a cyst in the body and tail the pancreas measuring 16 cm in maximal diameter | Mm768 | Mucinous cystic neoplasm (MCN) of the pancreas • high-grade dysplasia with an associated minimally invasive carcinoma |
|
| A 75-year-old woman with a multi-septated • low attenuation cyst in the head of the pancreas that has grown from 5 cm to 15 cm in size for 6 years. | Mm768 | Serous cystadenoma • microcystic |
|
| A 52-year-old woman with past medical history notable for Von Hippel Lindau (VHL) syndrome with multiple left renal cell carcinomas s/p left radical nephrectomy and right renal cell carcinoma s/p right partial nephrectomy presented for surgical evaluation in the setting of multiple pancreatic cysts and recently discovered pancreatic body mass. | Mm768 | Mixed serous-neuroendocrine neoplasm arising in association with Von Hippel Lindau syndrome |
|
| A 35-year-old woman with an incidentally discovered 4 cm cyst in the distal pancreas | Mm768 | Acinar cystic transformation of the pancreas |
|
| A 63-year-old man with an incidentally found a 4 cm pancreatic tail cyst | Mm768 | Lymphoepithelial cyst (LEC) |
|
| A 19-year-old woman with an incidentally found cystic lesion in the tail of pancreas | Mm768 | Enteric duplication cyst of the pancreas |
|
| A 20-year-old woman presented with abdominal pain related to menstrual cycle and was found to have a 4 cm cyst in the pancreatic tail on imaging. | Mm768 | Endometriosis of the pancreas |
|
| A 81-year-old woman developed abdominal pain • vomiting and diarrhea a month before the operation and was found to have elevated liver enzymes (a total bilirubin of 2.6 • alkaline phosphatase of 506 • ALT 493 and AST. | Mm768 | Autoimmune pancreatitis • type 1 |
|
| A 53-year-old male with an incidental finding of a potentially early pancreatic cancer in the pancreatic body | Mm768 | Autoimmune pancreatitis • type 2 |
|
| A 57-year-old woman with alcohol abuse in the past presented with recurrent episodes of pancreatitis and was found to have a 4 cm mass involving the head of the pancreas. | Mm768 | Groove pancreatitis |
