Sign-Out Tools: Breast
Contents
[hide]Coded Comments
Code | Comment |
---|---|
IDC | Invasive ductal carcinoma |
ILC | Invasive lobular carcinoma |
DCIS | Ductal carcinoma in‐situ |
DCIS1 | Ductal carcinoma in‐situ, grade 1 |
DCIS2 | Ductal carcinoma in‐situ, grade 2 |
DCIS3 | Ductal carcinoma in‐situ, grade 2 |
ADH | Atypical ductal hyperplasia |
FEA | Flat epithelial atypia |
LCIS | Lobular neoplasia (lobular carcinoma in‐situ) |
ALH | Lobular neoplasia (atypical lobular hyperplasia) |
FBA | Fibroadenoma |
PASH | Pseudoangiomatous stromal hyperplasia |
FCC | Fibrocystic changes |
UDH | Usual ductal hyperplasia |
SCA | Sclerosing adenosis |
BDA | Blunt duct adenosis |
RADS | Radial scar |
HBX | Healing biopsy site |
XRT | Changes consistent with prior irradiation |
CALC | Calcifications |
CALC | Calcifications |
ITC | Isolated tumor cells |
KER1 | Immunostained slides for cytokeratin AE1.3/Cam5.2, cytokeratin 7, and cytokeratin MNF116 were
examined on tissue levels. |
KER2 | Immunostained slides for cytokeratin AE1.3/Cam5.2, cytokeratin 7, and cytokeratin MNF116 were
examined on tissue levels from each of 2 blocks. |
KER3 | Immunostained slides for cytokeratin AE1.3/Cam5.2, cytokeratin 7, and cytokeratin MNF116 were
examined on tissue levels from each of 3 blocks. |
GRDNR | The tumor grade in this limited sample may not be representative of the entire lesion. |
BRADS | The results of immunohistochemical staining for estrogen receptor, progesterone receptor, and
Her2/neu protein expression and of fluorescence in‐situ hybridization studies for Her2/neu gene amplification will be reported in an addendum. |
ERPR | Note: The results of immunohistochemical staining for estrogen and progesterone receptors will
be reported in an addendum. |
MARG | NOTE: The resection margins of the specimen(s) were inked and microscopically evaluated; see
individual gross descriptions. |
MARG1 | NOTE: The resection margins of the specimen were inked and microscopically evaluated. |
MARG2 | NOTE: The resection margins of the specimens were inked and microscopically evaluated. |
MULTI | The patient’s chart and available radiographs were reviewed at the MGH Breast Center
multidisciplinary conference. |
EEEEE | This case does not contain all the coding components for CMS PQRI measure #99. |
Grading Chart: Ductal Carcinoma In-situ Grading
Pleomorphic nuclei | ||
---|---|---|
Abundant central necrosis | Present | Absent |
Present | Grade 3 | Grade 2 |
Absent | Grade 3 | Grade 1 |
Rauramo et al.: The effect of castration and peroral estrogen therapy on some psychological functions. Front Horm Res 1975;3:94-104. PMID: 1234567
Grading Chart: Invasive Carcinoma Grading
Score | Tubule Formation | Nuclear Pleomorphism | Mitotic Count* |
---|---|---|---|
1 | More than 75 % | Slight | 0 - 8 |
2 | 10% - 75% | Moderate | 9 - 17 |
3 | Less than 10% | Marked | 18 or greater |
* per 10 high power field with 40X objective and 10X ocular with a Field Diameter = 0.55 mm. A field diameter of 0.55 mm is assumed for this table and is compatable with sign-out booth Olympus microscopes. Please confirm that the field diameter of your microscope is 0.55 mm before using the above chart. For other field diameters, please see the conversion chart below.
Total Score | Interpretation |
---|---|
3-5 | Grade 1 (Low Grade) |
6-7 | Grade 2 (Intermediate Grade) |
8-9 | Grade 3 (High Grade) |
Score Categories According to Field Diameter and Mitotic Count
Table of mitosis score thresholds by Field Diameter (mm) | ||||
---|---|---|---|---|
Field Diameter (mm) | Field Area (mm2 | Number of Mitoses per 10 Fields | ||
Score 1 | Score 2 | Score 3 | ||
0.50 | 0.196 | ≤7 | 8 to 14 | ≥15 |
0.51 | 0.204 | ≤7 | 8 to 14 | ≥15 |
0.52 | 0.212 | ≤7 | 8 to 15 | ≥16 |
0.53 | 0.221 | ≤8 | 9 to 16 | ≥17 |
0.54 | 0.229 | ≤8 | 9 to 16 | ≥17 |
0.55 | 0.238 | ≤8 | 9 to 17 | ≥18 |
0.56 | 0.246 | ≤8 | 9 to 17 | ≥18 |
0.57 | 0.255 | ≤9 | 10 to 18 | ≥19 |
0.58 | 0.264 | ≤9 | 10 to 19 | ≥20 |
0.59 | 0.273 | ≤9 | 10 to 19 | ≥20 |
0.60 | 0.283 | ≤10 | 11 to 20 | ≥21 |
References
- Jump up ↑ Citation: Silverstein et al.: Prognostic classification of breast ductal carcinoma-in-situ. Lancet 1995;345:1154-7. PMID: 7723550
Abstract - Jump up ↑ Citation: Robbins et al.: Histological grading of breast carcinomas: a study of interobserver agreement. Hum. Pathol. 1995;26:873-9. PMID: 7635449
Abstract