Difference between revisions of "DZI20-210-Case-21"
From MGH Learn Pathology
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IHC: atypical lymphocytes are negative for CD4 and CD8, expressing a gamma-delta T cell phenotype, positive for CD3 and CD7 with partial loss of CD5 expression. CD56 is negative; partial expression of TIA-1 and granzyme B is noted. BF1 (alpha/beta TCR) is negative. Numerous large cells are positive for CD30 (15%). In situ hybridization for EBV remained negative. Molecular analysis revealed a clonal rearrangement of the T cell gamma receptor. | IHC: atypical lymphocytes are negative for CD4 and CD8, expressing a gamma-delta T cell phenotype, positive for CD3 and CD7 with partial loss of CD5 expression. CD56 is negative; partial expression of TIA-1 and granzyme B is noted. BF1 (alpha/beta TCR) is negative. Numerous large cells are positive for CD30 (15%). In situ hybridization for EBV remained negative. Molecular analysis revealed a clonal rearrangement of the T cell gamma receptor. | ||
|reasonCode=NA | |reasonCode=NA | ||
| − | |subject= | + | |subject=MGH |
| − | |performer= | + | |performer=VN048 |
|authoredOn=October 21, 2020 03:15:36 PM | |authoredOn=October 21, 2020 03:15:36 PM | ||
|requester=Vn048 | |requester=Vn048 | ||
|sequence=21 | |sequence=21 | ||
| + | |access=public | ||
}} | }} | ||
{{Media | {{Media | ||
