Difference between revisions of "DZI19-175-Case-3"

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Two days later, after RBCs and fluids: WBC: 8.1; HGB: 9.2; HCT: 25.2; MCV: 85 fL; PLT: 250 (Diff: 47% polys; 29% lymphs;  7% monos; 8% blasts; 7% eos; 2% basos; 2% metas  Bone marrow biopsy (HE, reticulin stain) and touch prep (clot). What is your differential diagnosis?
 
Two days later, after RBCs and fluids: WBC: 8.1; HGB: 9.2; HCT: 25.2; MCV: 85 fL; PLT: 250 (Diff: 47% polys; 29% lymphs;  7% monos; 8% blasts; 7% eos; 2% basos; 2% metas  Bone marrow biopsy (HE, reticulin stain) and touch prep (clot). What is your differential diagnosis?
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|authoredOn=October 24, 2019 11:51:00 PM
 
|authoredOn=October 24, 2019 11:51:00 PM
 
|requester=Sac11
 
|requester=Sac11
 
|sequence=3
 
|sequence=3
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|access=public
 
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Revision as of 16:11, June 21, 2022

DZI19-175-Case-3
20-month old boy with splenomegaly, thrombocytosis, severe anemia and peripheral blasts

WBC: 29.6; HGB: 4.7; HCT: 13.4%; MCV: 85.9 fL; PLT: 900 (Diff: 36% polys; 30% lymphs; 12% monos; 6% eos; 2% basos; 1% myelocytes; 13% blasts; 12 nRBCs/100WBC). Peripheral blood smear. What is your differential diagnosis?

Two days later, after RBCs and fluids: WBC: 8.1; HGB: 9.2; HCT: 25.2; MCV: 85 fL; PLT: 250 (Diff: 47% polys; 29% lymphs; 7% monos; 8% blasts; 7% eos; 2% basos; 2% metas Bone marrow biopsy (HE, reticulin stain) and touch prep (clot). What is your differential diagnosis?
Juvenile chronic myelomonocytic leukemia (JMML), with some atypical features in the setting of neurofibromatosis type I
December 31, 1969 7:00:00 PM





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