Difference between revisions of "DZI20-206-Case-13"
From MGH Learn Pathology
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Note: The biopsy demonstrates hepatic parenchyma with <10% macrovesicular steatosis. Evaluation of microvesicular steatosis is limited by frozen artifact. Diagnostic features of steatohepatitis are not present. Occasional portal tracts demonstrate mild expansion. No necrosis is present. A trichrome stain highlights patchy mild sinusoidal fibrosis throughout the lobules. Iron stain is negative for stainable iron, and a PAS/D stain is negative for PAS-positive globules. | Note: The biopsy demonstrates hepatic parenchyma with <10% macrovesicular steatosis. Evaluation of microvesicular steatosis is limited by frozen artifact. Diagnostic features of steatohepatitis are not present. Occasional portal tracts demonstrate mild expansion. No necrosis is present. A trichrome stain highlights patchy mild sinusoidal fibrosis throughout the lobules. Iron stain is negative for stainable iron, and a PAS/D stain is negative for PAS-positive globules. | ||
| − | Frozen Part B: Liver with <10% macrovesicular steatosis and <10% microvesicular steatosis, midzonal cholestasis, focal mild lymphocytic inflammation, bile ductular proliferation, and | + | Frozen Part B: Liver with <10% macrovesicular steatosis and <10% microvesicular steatosis, midzonal cholestasis, focal mild lymphocytic inflammation, bile ductular proliferation, and broad portal expansion with foci s/f bridging fibrosis. |
Permanent Part B: Liver with cholestatic features, focal hepatocyte degeneration, and variable fibrosis (see note). | Permanent Part B: Liver with cholestatic features, focal hepatocyte degeneration, and variable fibrosis (see note). | ||
Revision as of 13:45, February 26, 2021
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