Difference between revisions of "DZI19-121-Case-7"

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Latest revision as of 13:23, December 9, 2024

DZI19-121-Case-7
23 year old woman with deep left cerebellar mass discovered incidentally on an MRI of the cervical spine obtained after a motor vehicle accident.
Integrated diagnosis:

DIFFUSE GLIOMA, BRAF V600E-MUTANT

Histological diagnosis: Diffuse astrocytoma

WHO (integrated histological and molecular) grade: undefined (likely II)

Molecular information: BRAF V600E: MUTANT (immunohistochemistry and sequencing) IDH: wildtype (IDH1/2 sequencing) P53: weak in rare tumor cells (immunohistochemistry, consistent with wildtype) ATRX: nuclear expression retained (immunohistochemistry, consistent with wildtype) MGMT promoter: methylated (PCR)

EGFR gene amplification: absent (FISH)
December 31, 1969 7:00:00 PM