Difference between revisions of "DZI19-121-Case-2"

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Latest revision as of 13:23, December 9, 2024

DZI19-121-Case-2
32 yo woman with 2 weeks of headaches and mild nausea when changing head position
Integrated diagnosis: ANAPLASTIC ASTROCYTOMA, IDH-MUTANT

Histological diagnosis: anaplastic gemistocytic astrocytoma

WHO histological grade: III

Molecular information: IDH: mutant (R132H, IDH1/2 PCR sequencing) P53: positive in most tumor cells (immunohistochemistry, consistent with mutation) ATRX: nuclear expression lost (immunohistochemistry, consistent with mutation)

MGMT promoter: methylated (methylation specific PCR)
December 31, 1969 7:00:00 PM