Difference between revisions of "DZI19-121-Case-10"
From MGH Learn Pathology
(Edited automatically from page DZI19-121.) |
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|order_date=September 11, 2019 01:58:41 PM | |order_date=September 11, 2019 01:58:41 PM | ||
|user=Em99 | |user=Em99 | ||
| + | |slide_stain=H&E | ||
|slide_anatomy=Show | |slide_anatomy=Show | ||
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|case_id=10 | |case_id=10 | ||
|clinical_hx=35 year old woman presents with new onset of tonic-clonic seizures | |clinical_hx=35 year old woman presents with new onset of tonic-clonic seizures | ||
| + | |case_diagnosis=Integrated diagnosis: | ||
| + | PLEOMOPHIC XANTHOASTROCYTOMA, BRAF V600E MUTANT | ||
| + | |||
| + | Histological diagnosis: Pleomorphic astrocytoma | ||
| + | |||
| + | WHO histological grade: II | ||
| + | |||
| + | Molecular information: | ||
| + | BRAF V600E: MUTANT (sequencing) | ||
| + | IDH: wildtype (IDH1/2 sequencing) | ||
| + | P53: weak in rare tumor cells (immunohistochemistry, consistent with wildtype) | ||
| + | ATRX: nuclear expression retained (immunohistochemistry, consistent with wildtype) | ||
}} | }} | ||
Revision as of 20:51, September 13, 2019
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