Difference between revisions of "DZI19-121-Case-3"
From MGH Learn Pathology
(Edited automatically from page DZI19-121.) |
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|case_id=3 | |case_id=3 | ||
|clinical_hx=45 year old man with a history of a “brain tumor” 10 years ago, now with headache and vision changes | |clinical_hx=45 year old man with a history of a “brain tumor” 10 years ago, now with headache and vision changes | ||
| + | |case_diagnosis=Integrated diagnosis: ANAPLASTIC ASTROCYTOMA, IDH-MUTANT | ||
| + | |||
| + | Histological diagnosis: Anaplastic astrocytoma (recurrent) | ||
| + | |||
| + | WHO histological grade: III | ||
| + | |||
| + | Molecular information: | ||
| + | IDH: MUTANT (R132H immunohistochemistry) | ||
| + | P53: positive in most tumor cells (immunohistochemistry, consistent with mutation) | ||
| + | ATRX: nuclear expression lost (immunohistochemistry, consistent with mutation) | ||
| + | CDKN2A/B: homozygous deletion PRESENT (NGS sequencing) | ||
}} | }} | ||
Revision as of 20:32, September 13, 2019
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