Difference between revisions of "DZI19-121-Case-2"
From MGH Learn Pathology
(Edited automatically from page DZI19-121.) |
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|case_id=2 | |case_id=2 | ||
|clinical_hx=32 yo woman with 2 weeks of headaches and mild nausea when changing head position | |clinical_hx=32 yo woman with 2 weeks of headaches and mild nausea when changing head position | ||
| + | |case_diagnosis=Integrated diagnosis: ANAPLASTIC ASTROCYTOMA, IDH-MUTANT | ||
| + | |||
| + | Histological diagnosis: anaplastic gemistocytic astrocytoma | ||
| + | |||
| + | WHO histological grade: III | ||
| + | |||
| + | Molecular information: | ||
| + | IDH: mutant (R132H, IDH1/2 PCR sequencing) | ||
| + | P53: positive in most tumor cells (immunohistochemistry, consistent with mutation) | ||
| + | ATRX: nuclear expression lost (immunohistochemistry, consistent with mutation) | ||
| + | MGMT promoter: methylated (methylation specific PCR) | ||
}} | }} | ||
{{dziMedia | {{dziMedia | ||
Revision as of 20:30, September 13, 2019
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