Difference between revisions of "DZI19-121-Case-4"

From MGH Learn Pathology
(Automatic edit to upgrade to new templates)
(Updating subject, access, and performer)
Line 22: Line 22:
 
EGFR amplification: PRESENT (FISH)
 
EGFR amplification: PRESENT (FISH)
 
|reasonCode=67 year old man with new onset of seizures
 
|reasonCode=67 year old man with new onset of seizures
|subject=public
+
|subject=MGH
|performer=Mml55
+
|performer=MML55
 
|authoredOn=September 11, 2019 01:57:55 PM
 
|authoredOn=September 11, 2019 01:57:55 PM
 
|requester=Em99
 
|requester=Em99
 
|sequence=4
 
|sequence=4
 +
|access=public
 
}}
 
}}
 
{{Media
 
{{Media

Revision as of 15:09, June 21, 2022

DZI19-121-Case-4
67 year old man with new onset of seizures
Integrated diagnosis:

DIFFUSE ASTROCYTIC GLIOMA, IDH-WILDTYPE, WITH MOLECULAR FEATURES OF GLIOBLASTOMA

Histological diagnosis: Anaplastic astrocytoma

WHO (integrated histological and molecular grade): IV

Molecular information: IDH: wildtype (IDH1/2 PCR sequencing) P53: positive in most tumor cells (immunohistochemistry, consistent with mutation) ATRX: nuclear expression retained (immunohistochemistry, consistent with wildtype) MGMT promoter: unmethylated (methylation specific PCR)

EGFR amplification: PRESENT (FISH)
December 31, 1969 7:00:00 PM