WSI21-76

Request details

Request type Outs

Subspecialty Hematopathology

Topic 2021/04/19

Presenter Hasserjian, Robert P.,MD

Date and time Monday, April 19, 2021 12:00 AM

Add more cases

Case	Clinical history	Requester
Case	Clinical history	Requester
Case 1	65 year-old woman with history of essential thrombocythemia for 4 years. Now marked increase in platelets. WBC 21.4 x 109/L (80% polys • 11% lymphs • 5% monos • 1% eos • 1% basos) • HGB 17.5 g/dL • PLT 1 • 415 x 109/L.	Rh27
Case 2	16 year-old female with history of ITP • now normal platelets but mild leukocytosis and rare circulating blasts. WBC 11.3 x 109/L (71% polys • 17% lymphs • 8% monos • 2% eos • 2% basos) • HGB 11.2 g/dL • PLT 199 x 109/L.	Rh27
Case 3	82 year-old female with history of chronic renal failure due to autoimmune disease; previous anemia of chronic disease on EPO therapy • now has become leukopenic and thrombocytopenic. WBC 0.6 x 109/L (23% polys • 66% lymphs • 11% eos) • HGB 6.7 g/dL • PLT 13 x 109/L.	Rh27
Case 4	47 year-old male. No history or CBC provided.	Rh27
Case 5	61 year-old male with lymphadenopathy • hepatosplenomegaly • and pancytopenia.	Rh27
Case 6	60 year-old male with leukocytosis • concern for CML. WBC 138.07 x 109/L (44% polys • 11% bands • 2% lymphs • 12% monos • 8% eos • 1% basos • 8% myelocytes • 8% metamyelocytes • 6% promyelocytes • 1% blasts) • HGB 7.8 g/dL • PLT 98 x 109/L.	Rh27
Case 7	67 year-old man with history of colon cancer post right hemicolectomy and chemotherapy • now found to have leukocytosis. WBC 30.4 x 109/L • HGB 8.6 g/dL • PLT 284 x 109/L. Karyotype normal. NGS shows ASXL1 p.Gln910Argfs*14 truncating mutation (VAF 10%).	Rh27