Difference between revisions of "mgh:cyto-1-7"
From MGH Learn Pathology
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== Basic cytomorphology == | == Basic cytomorphology == | ||
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| − | '''Cytology Respiratory Specimens –MN05-J8970''' | + | '''Cytology Respiratory Specimens –MN05-J8970'''| |
* Sputum | * Sputum | ||
* Bronchial washing and brushings | * Bronchial washing and brushings | ||
* Bronchoalveolar lavage (BAL) | * Bronchoalveolar lavage (BAL) | ||
* Fine needle aspirations (FNA) | * Fine needle aspirations (FNA) | ||
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| − | '''Normal Respiratory Cytology –MN05-X13303''' | + | '''Normal Respiratory Cytology –MN05-X13303'''| |
* Squamous cells (oral contamination) | * Squamous cells (oral contamination) | ||
* Glandular cells | * Glandular cells | ||
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* Pneumocytes | * Pneumocytes | ||
* Alveolar macrophages | * Alveolar macrophages | ||
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| − | '''Alveolar macrophages –MN06-M2366''' | + | '''Alveolar macrophages –MN06-M2366'''| |
* Oval to bean shaped nuclei | * Oval to bean shaped nuclei | ||
* Mononucleated or multinucleated | * Mononucleated or multinucleated | ||
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* siderophages | * siderophages | ||
* lipophages(associated with aspiration pneumonia) | * lipophages(associated with aspiration pneumonia) | ||
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| − | '''Granulomatous Inflammation –MN05-F5872''' | + | '''Granulomatous Inflammation –MN05-F5872'''| |
* Seen in pt’s with TB, Sarcoid and Rheumatoid Arthritis. | * Seen in pt’s with TB, Sarcoid and Rheumatoid Arthritis. | ||
* Can see giant cells | * Can see giant cells | ||
* Nodular collections of epithelioid histiocytes | * Nodular collections of epithelioid histiocytes | ||
* Cells with elongated nuclei with pale chromatin and tiny nucleoli | * Cells with elongated nuclei with pale chromatin and tiny nucleoli | ||
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| − | '''Chondroid Hamartoma–C03-C14116''' | + | '''Chondroid Hamartoma–C03-C14116'''| |
* Cartilage | * Cartilage | ||
* mature - homogenous, waxy | * mature - homogenous, waxy | ||
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* small bland bronchial cells | * small bland bronchial cells | ||
* Respiratory Infection –MN08-F9275 and N12-9869 | * Respiratory Infection –MN08-F9275 and N12-9869 | ||
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| − | '''Candida and Actinomyces from oral contamination''' | + | '''Candida and Actinomyces from oral contamination'''| |
* Aspergillus | * Aspergillus | ||
* 45º angle branching of true septate | * 45º angle branching of true septate | ||
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* broad, irregular ribbon-like hyphae | * broad, irregular ribbon-like hyphae | ||
* folding of hyphae | * folding of hyphae | ||
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| − | '''Squamous Cell Carcinoma –C92-8306 and MN06-324''' | + | '''Squamous Cell Carcinoma –C92-8306 and MN06-324'''| |
* Keratinizing (Well-Diff)/ Nonkeratinizing(Mod to poorly Diff) | * Keratinizing (Well-Diff)/ Nonkeratinizing(Mod to poorly Diff) | ||
* Bizarre cell shapes | * Bizarre cell shapes | ||
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* Coarsely granular and/or opaque nucleus | * Coarsely granular and/or opaque nucleus | ||
* Nucleoli possible | * Nucleoli possible | ||
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| − | '''Bronchogenic adenocarcinoma –C00-A43961''' | + | '''Bronchogenic adenocarcinoma –C00-A43961'''| |
* 3-D balls, single cells, syncytia | * 3-D balls, single cells, syncytia | ||
* Lacy, fine, vacuolated cytoplasm | * Lacy, fine, vacuolated cytoplasm | ||
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* Finely granular irregular chromatin | * Finely granular irregular chromatin | ||
* Nucleoli | * Nucleoli | ||
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| − | '''Bronchioloalveolar Carcinoma –C01-W33204''' | + | '''Bronchioloalveolar Carcinoma –C01-W33204'''| |
* 3-D balls, papillary growth | * 3-D balls, papillary growth | ||
* Finely granular to clear cytoplasm | * Finely granular to clear cytoplasm | ||
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* Intranuclear cytoplasmic invaginations | * Intranuclear cytoplasmic invaginations | ||
* Psammoma bodies may be seen | * Psammoma bodies may be seen | ||
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| − | '''Small Cell Carcinoma –C03-T32870 and MN04-G5451''' | + | '''Small Cell Carcinoma –C03-T32870 and MN04-G5451'''| |
* Single and syncytial | * Single and syncytial | ||
* Nuclear molding | * Nuclear molding | ||
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* Crush artifact ( nuclear DNA streaming) | * Crush artifact ( nuclear DNA streaming) | ||
* One to four times the size of a lymphocyte | * One to four times the size of a lymphocyte | ||
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| − | '''Carcinoid –C02-M34743''' | + | '''Carcinoid –C02-M34743'''| |
* Uniform cuboidal cells | * Uniform cuboidal cells | ||
* Scant to moderate cytoplasm | * Scant to moderate cytoplasm | ||
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* Small nucleoli possible | * Small nucleoli possible | ||
* Small blood vessels in background | * Small blood vessels in background | ||
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| − | '''Metastatic malignancy –MN07-T9423, MN07-T9423 and C97-B18744''' | + | '''Metastatic malignancy –MN07-T9423, MN07-T9423 and C97-B18744'''| |
* Compare the metastatic with the primary lesion | * Compare the metastatic with the primary lesion | ||
* Usually no tumor diathesis | * Usually no tumor diathesis | ||
* Presence of multiple nodules and a history of morphologically compatible cancer strongly favor metastasis | * Presence of multiple nodules and a history of morphologically compatible cancer strongly favor metastasis | ||
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{{:mgh:cytology-footer}} | {{:mgh:cytology-footer}} | ||
Revision as of 15:38, July 2, 2020
Contents
[hide]Lectures
- Lecture: Respiratory cytology, part 1 by Dr. WS Black-Schaffer
- Lecture: Respiratory cytology, part 2. by Dr. W.S. Black-Schaffer
- Indications for cytology examination
- Procuring the specimen
- Test platforms/specimen processing and triage
- Report
Basic cytomorphology
Cytology Respiratory Specimens –MN05-J8970
Normal Respiratory Cytology –MN05-X13303
Alveolar macrophages –MN06-M2366
Granulomatous Inflammation –MN05-F5872
Chondroid Hamartoma–C03-C14116
Candida and Actinomyces from oral contamination
Squamous Cell Carcinoma –C92-8306 and MN06-324
Bronchogenic adenocarcinoma –C00-A43961
Bronchioloalveolar Carcinoma –C01-W33204
Small Cell Carcinoma –C03-T32870 and MN04-G5451
Carcinoid –C02-M34743
Metastatic malignancy –MN07-T9423, MN07-T9423 and C97-B18744
