Difference between revisions of "DZI19-175-Case-3"
From MGH Learn Pathology
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|case_id=3 | |case_id=3 | ||
|publish_timestamp=2019/11/01 13:00 | |publish_timestamp=2019/11/01 13:00 | ||
| − | |clinical_hx= | + | |clinical_hx=20-month old boy with splenomegaly, thrombocytosis, severe anemia and peripheral blasts |
| − | + | ||
| − | + | WBC: 29.6; HGB: 4.7; HCT: 13.4%; MCV: 85.9 fL; PLT: 900 (Diff: 36% polys; 30% lymphs; 12% monos; 6% eos; 2% basos; 1% myelocytes; 13% blasts; 12 nRBCs/100WBC). Peripheral blood smear. What is your differential diagnosis? | |
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| + | Two days later, after RBCs and fluids: WBC: 8.1; HGB: 9.2; HCT: 25.2; MCV: 85 fL; PLT: 250 (Diff: 47% polys; 29% lymphs; 7% monos; 8% blasts; 7% eos; 2% basos; 2% metas Bone marrow biopsy (HE, reticulin stain) and touch prep (clot). What is your differential diagnosis? | ||
|case_diagnosis=Juvenile chronic myelomonocytic leukemia (JMML), with some atypical features in the setting of neurofibromatosis type I | |case_diagnosis=Juvenile chronic myelomonocytic leukemia (JMML), with some atypical features in the setting of neurofibromatosis type I | ||
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Revision as of 16:21, October 26, 2019
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