Difference between revisions of "DZI19-175-Case-3"

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|dziorder=DZI19-175
 
|dziorder=DZI19-175
 
|case_id=3
 
|case_id=3
|publish_timestamp=Choose_date 13:00
+
|publish_timestamp=2019/11/01 13:00
 
|clinical_hx=: 20-month old boy with splenomegaly, thrombocytosis, severe anemia and peripheral blasts
 
|clinical_hx=: 20-month old boy with splenomegaly, thrombocytosis, severe anemia and peripheral blasts
 
   WBC: 29.6; HGB: 4.7; HCT: 13.4%; MCV: 85.9 fL; PLT: 900 (Diff: 36% polys; 30% lymphs; 12% monos; 6% eos; 2% basos; 1% myelocytes; 13% blasts;  12 nRBCs/100WBC).  Peripheral blood smear. What is your differential diagnosis?
 
   WBC: 29.6; HGB: 4.7; HCT: 13.4%; MCV: 85.9 fL; PLT: 900 (Diff: 36% polys; 30% lymphs; 12% monos; 6% eos; 2% basos; 1% myelocytes; 13% blasts;  12 nRBCs/100WBC).  Peripheral blood smear. What is your differential diagnosis?
 
       Two days later, after RBCs and fluids: WBC: 8.1; HGB: 9.2; HCT: 25.2; MCV: 85 fL; PLT: 250 (Diff: 47% polys; 29% lymphs;  7% monos; 8% blasts; 7% eos; 2% basos; 2% metas  Bone marrow biopsy (HE, reticulin stain) and touch prep (clot). What is your differential diagnosis?
 
       Two days later, after RBCs and fluids: WBC: 8.1; HGB: 9.2; HCT: 25.2; MCV: 85 fL; PLT: 250 (Diff: 47% polys; 29% lymphs;  7% monos; 8% blasts; 7% eos; 2% basos; 2% metas  Bone marrow biopsy (HE, reticulin stain) and touch prep (clot). What is your differential diagnosis?
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|case_diagnosis=Juvenile chronic myelomonocytic leukemia (JMML), with some atypical features in the setting of neurofibromatosis type I
 
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Revision as of 19:02, October 24, 2019



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