Difference between revisions of "DZI20-210-Case-21"

From MGH Learn Pathology
(Automatic edit to upgrade to new templates)
(Added status template)
 
(One intermediate revision by the same user not shown)
Line 12: Line 12:
 
IHC: atypical lymphocytes are negative for CD4 and CD8, expressing a gamma-delta T cell phenotype, positive for CD3 and CD7 with partial loss of CD5 expression. CD56 is negative; partial expression of TIA-1 and granzyme B is noted. BF1 (alpha/beta TCR) is negative. Numerous large cells are positive for CD30 (15%). In situ hybridization for EBV remained negative. Molecular analysis revealed a clonal rearrangement of the T cell gamma receptor.
 
IHC: atypical lymphocytes are negative for CD4 and CD8, expressing a gamma-delta T cell phenotype, positive for CD3 and CD7 with partial loss of CD5 expression. CD56 is negative; partial expression of TIA-1 and granzyme B is noted. BF1 (alpha/beta TCR) is negative. Numerous large cells are positive for CD30 (15%). In situ hybridization for EBV remained negative. Molecular analysis revealed a clonal rearrangement of the T cell gamma receptor.
 
|reasonCode=NA
 
|reasonCode=NA
|subject=public
+
|subject=MGH
|performer=Vn048
+
|performer=VN048
 
|authoredOn=October 21, 2020 03:15:36 PM
 
|authoredOn=October 21, 2020 03:15:36 PM
 
|requester=Vn048
 
|requester=Vn048
 
|sequence=21
 
|sequence=21
 +
|access=public
 
}}
 
}}
 
{{Media
 
{{Media
Line 30: Line 31:
 
|subject=Z0FBQUFBQmZrRkNiR1FUMG14U0JkN3ROU2p5Z2s3VHg5c1oyX0dYR3JvUHV5V29xaW03aWlNRmVmdm9mNnFFYzBKa3pydmc1ZjhNZnQyaUR6M1NSeTlrN0JJbVU2bUdid3c9PQ
 
|subject=Z0FBQUFBQmZrRkNiR1FUMG14U0JkN3ROU2p5Z2s3VHg5c1oyX0dYR3JvUHV5V29xaW03aWlNRmVmdm9mNnFFYzBKa3pydmc1ZjhNZnQyaUR6M1NSeTlrN0JJbVU2bUdid3c9PQ
 
|modality=mrxs
 
|modality=mrxs
 +
}}
 +
{{status
 +
|status=active
 +
|requester=Vn048
 +
|authoredOn=October 21, 2020 03:15:36 PM
 
}}
 
}}

Latest revision as of 14:01, December 9, 2024

DZI20-210-Case-21
NA
SKIN, LEFT LATERAL THIGH, SHAVE BIOPSY, GAMMA DELTA T CELL LYMPHOMA. IHC: atypical lymphocytes are negative for CD4 and CD8, expressing a gamma-delta T cell phenotype, positive for CD3 and CD7 with partial loss of CD5 expression. CD56 is negative; partial expression of TIA-1 and granzyme B is noted. BF1 (alpha/beta TCR) is negative. Numerous large cells are positive for CD30 (15%). In situ hybridization for EBV remained negative. Molecular analysis revealed a clonal rearrangement of the T cell gamma receptor.
December 31, 1969 7:00:00 PM