Difference between revisions of "DZI20-210-Case-21"

From MGH Learn Pathology
(Created page with "{{dziCase |order_date=October 21, 2020 03:15:36 PM |user=Vn048 |dziorder=DZI20-210 |case_id=21 |publish_timestamp=Choose_date 13:00 |clinical_hx=NA |case_diagnosis=SKIN, LEFT...")
 
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{{dziCase
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{{ServiceRequestCase
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|order_date=October 21, 2020 03:15:36 PM
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|identifier=DZI20-210-Case-21
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|user=Vn048
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|intent=order
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|dziorder=DZI20-210
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|category=409073007
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|case_id=21
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|publish_timestamp=Choose_date 13:00
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|orderDetail=case
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|case_diagnosis=SKIN, LEFT LATERAL THIGH, SHAVE BIOPSY, GAMMA DELTA T CELL LYMPHOMA.
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|supportingInfo=SKIN, LEFT LATERAL THIGH, SHAVE BIOPSY, GAMMA DELTA T CELL LYMPHOMA.
  
 
IHC: atypical lymphocytes are negative for CD4 and CD8, expressing a gamma-delta T cell phenotype, positive for CD3 and CD7 with partial loss of CD5 expression. CD56 is negative; partial expression of TIA-1 and granzyme B is noted. BF1 (alpha/beta TCR) is negative. Numerous large cells are positive for CD30 (15%). In situ hybridization for EBV remained negative. Molecular analysis revealed a clonal rearrangement of the T cell gamma receptor.
 
IHC: atypical lymphocytes are negative for CD4 and CD8, expressing a gamma-delta T cell phenotype, positive for CD3 and CD7 with partial loss of CD5 expression. CD56 is negative; partial expression of TIA-1 and granzyme B is noted. BF1 (alpha/beta TCR) is negative. Numerous large cells are positive for CD30 (15%). In situ hybridization for EBV remained negative. Molecular analysis revealed a clonal rearrangement of the T cell gamma receptor.
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|reasonCode=NA
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|subject=MGH
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|performer=VN048
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|authoredOn=October 21, 2020 03:15:36 PM
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|requester=Vn048
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|sequence=21
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|access=public
 
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|order_date=October 21, 2020 03:15:36 PM
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|identifier=DZI20-210-Case-21_1
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Latest revision as of 14:01, December 9, 2024

DZI20-210-Case-21
NA
SKIN, LEFT LATERAL THIGH, SHAVE BIOPSY, GAMMA DELTA T CELL LYMPHOMA. IHC: atypical lymphocytes are negative for CD4 and CD8, expressing a gamma-delta T cell phenotype, positive for CD3 and CD7 with partial loss of CD5 expression. CD56 is negative; partial expression of TIA-1 and granzyme B is noted. BF1 (alpha/beta TCR) is negative. Numerous large cells are positive for CD30 (15%). In situ hybridization for EBV remained negative. Molecular analysis revealed a clonal rearrangement of the T cell gamma receptor.
December 31, 1969 7:00:00 PM






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