Difference between revisions of "mgh:cyto-1-13"
From MGH Learn Pathology
(Created page with "'''1-13 Adrenal: R Tambouret MD, E Brachtel MD, R Arpin CT''' * Indications for cytology examination * Procuring the specimen * Test platforms/specimen processing and triage *...") |
|||
| (4 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
| − | + | __NOCACHE__{{DISPLAYTITLE:1-13 Adrenal: R Tambouret MD, E Brachtel MD, R Arpin CT}}{{:TOC}} | |
| + | <br> | ||
* Indications for cytology examination | * Indications for cytology examination | ||
* Procuring the specimen | * Procuring the specimen | ||
| Line 6: | Line 7: | ||
<br> | <br> | ||
| − | + | == Basic cytomorphology == | |
| − | + | {{collapsed| | |
| − | + | '''Normal adrenal cells – N13-6084'''| | |
| − | '''Normal adrenal cells – N13-6084''' | ||
* Variable Cellularity | * Variable Cellularity | ||
* Cortex: | * Cortex: | ||
| Line 19: | Line 19: | ||
** Large eccentric nucleus with fine chromatin | ** Large eccentric nucleus with fine chromatin | ||
** Conspicuous nucleoli | ** Conspicuous nucleoli | ||
| − | + | ||
Adrenal cortical nodules (hyperplastic, adenomas) | Adrenal cortical nodules (hyperplastic, adenomas) | ||
* Usually indistinguishable from benign cortical cells | * Usually indistinguishable from benign cortical cells | ||
| − | + | |}} | |
| − | + | {{collapsed| | |
| − | '''Pheochromocytoma – C91-C20757''' | + | '''Pheochromocytoma – C91-C20757'''| |
* Loosely cohesive round/plasmacytoid to spindled cells | * Loosely cohesive round/plasmacytoid to spindled cells | ||
* Fibrillary cytoplasm, oval hyperchromatic nuclei - may show anisonucleosis/pleomorphism/binucleation | * Fibrillary cytoplasm, oval hyperchromatic nuclei - may show anisonucleosis/pleomorphism/binucleation | ||
| Line 32: | Line 32: | ||
* Synaptophysin, chromogranin positive; S-100 positive in spindle cells | * Synaptophysin, chromogranin positive; S-100 positive in spindle cells | ||
* MIMICS: Adrenal cortical carcinoma, other poorly differentiated malignancies | * MIMICS: Adrenal cortical carcinoma, other poorly differentiated malignancies | ||
| − | + | |}} | |
| − | + | {{collapsed| | |
| − | '''Adrenal cortical carcinoma – C99-T12804''' | + | '''Adrenal cortical carcinoma – C99-T12804'''| |
* May not be able to diagnose on cytology alone, but may suspect if mitoses, necrosis or marked pleomorphism is present | * May not be able to diagnose on cytology alone, but may suspect if mitoses, necrosis or marked pleomorphism is present | ||
Histological assessment required to distinguish larger adenomas from carcinomas | Histological assessment required to distinguish larger adenomas from carcinomas | ||
| − | + | |}} | |
| − | + | {{collapsed| | |
| − | '''Metastases –N13-6638, C95-N3969 and C97-R25603''' | + | '''Metastases –N13-6638, C95-N3969 and C97-R25603'''| |
* cell population resembling primary tumor | * cell population resembling primary tumor | ||
| + | |}} | ||
| + | {{:mgh:cytology-footer}} | ||
Latest revision as of 15:43, July 2, 2020
Contents
[hide]
- Indications for cytology examination
- Procuring the specimen
- Test platforms/specimen processing and triage
- Report
Basic cytomorphology
Normal adrenal cells – N13-6084
Pheochromocytoma – C91-C20757
Adrenal cortical carcinoma – C99-T12804
Metastases –N13-6638, C95-N3969 and C97-R25603
