Difference between revisions of "DZI19-175-Case-3"

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{{ServiceRequestCase
|order_date=October 24, 2019 11:51:00 PM
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|identifier=DZI19-175-Case-3
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|supportingInfo=Juvenile chronic myelomonocytic leukemia (JMML), with some atypical features in the setting of neurofibromatosis type I
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|reasonCode=20-month old boy with splenomegaly, thrombocytosis, severe anemia and peripheral blasts
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WBC: 29.6; HGB: 4.7; HCT: 13.4%; MCV: 85.9 fL; PLT: 900 (Diff: 36% polys; 30% lymphs; 12% monos; 6% eos; 2% basos; 1% myelocytes; 13% blasts;  12 nRBCs/100WBC).  Peripheral blood smear. What is your differential diagnosis?
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Two days later, after RBCs and fluids: WBC: 8.1; HGB: 9.2; HCT: 25.2; MCV: 85 fL; PLT: 250 (Diff: 47% polys; 29% lymphs;  7% monos; 8% blasts; 7% eos; 2% basos; 2% metas  Bone marrow biopsy (HE, reticulin stain) and touch prep (clot). What is your differential diagnosis?
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|subject=MGH
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  WBC: 29.6; HGB: 4.7; HCT: 13.4%; MCV: 85.9 fL; PLT: 900 (Diff: 36% polys; 30% lymphs; 12% monos; 6% eos; 2% basos; 1% myelocytes; 13% blasts;  12 nRBCs/100WBC).  Peripheral blood smear. What is your differential diagnosis?
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|createdDateTime=October 24, 2019 11:51:00 PM
      Two days later, after RBCs and fluids: WBC: 8.1; HGB: 9.2; HCT: 25.2; MCV: 85 fL; PLT: 250 (Diff: 47% polys; 29% lymphs;  7% monos; 8% blasts; 7% eos; 2% basos; 2% metas  Bone marrow biopsy (HE, reticulin stain) and touch prep (clot). What is your differential diagnosis?
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Latest revision as of 13:25, December 9, 2024

DZI19-175-Case-3
20-month old boy with splenomegaly, thrombocytosis, severe anemia and peripheral blasts

WBC: 29.6; HGB: 4.7; HCT: 13.4%; MCV: 85.9 fL; PLT: 900 (Diff: 36% polys; 30% lymphs; 12% monos; 6% eos; 2% basos; 1% myelocytes; 13% blasts; 12 nRBCs/100WBC). Peripheral blood smear. What is your differential diagnosis?

Two days later, after RBCs and fluids: WBC: 8.1; HGB: 9.2; HCT: 25.2; MCV: 85 fL; PLT: 250 (Diff: 47% polys; 29% lymphs; 7% monos; 8% blasts; 7% eos; 2% basos; 2% metas Bone marrow biopsy (HE, reticulin stain) and touch prep (clot). What is your differential diagnosis?
Juvenile chronic myelomonocytic leukemia (JMML), with some atypical features in the setting of neurofibromatosis type I
December 31, 1969 7:00:00 PM