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Latest revision as of 11:45, December 8, 2025


Request type AP didactic (409073007) - MGH
Subspecialty Academic
Set Grand Rounds
Topic Grand Rounds
Presenter Tashman, Joshua W.,MD, PhD
Date and time Thursday, December 11, 2025 12:00 PM



Case Clinical history Requester
Case Clinical history Requester

Case 1


Man in his late 70s without relevant cancer history. He presents with a palpable testicular mass (~1.5-2 cm). Serum markers are negative and there is no evidence of extratesticular disease. A radical orchiectomy is performed. Em99

Case 2


2-month-old baby boy with a relatively large sonographically complex testicular mass. Serum markers are negative. A radical orchiectomy is performed. Em99

Case 3


34-year-old man with small (~1.4 cm) self-discovered testicular painless tumor. Serum markers are unavailable. A radical orchiectomy was performed. Em99

Case 4


37 y.o. man with a history of testicular GCT containing teratoma “somatic-type” RMS and ENET s/p orchiectomy + RPLND. Developed post-orchiectomy/RPLND recurrence treated with Etoposide + cisplatin + ifosfamide followed by Copanlesib (tumor showed a pathogenic PIK3CA variant). A complex multiorgan resection is performed to excise a large residual retroperitoneal mass. Em99

Case 5


46-year-old man presenting with left testicular mixed germ cell tumor liver and lung metastases and retrperitoneal/pelvic masses encasing the left ureter. Status post VIP salvage TIP and high dose intensified chemotherapy. Residual retroperitoneal and pelvic masses are resected. A section of the pelvic mass is provided. Em99

Case 6


26 year old patient with a paratesticular tumor involving epididymis. A resection of the lesion was performed at the time of bilateral vasectomy. Em99

Case 7


Elderly man with a complex clinical history. He has a diagnosis of pulmonary sarcoidosis treated with prednisone and multiple episodes of pneumonia (after initiation of steroids). He now presents with a palpable testicular mass concerning for malignancy. Em99

Case 8


Middle aged man with a remote history of a testicular tumor (> 5 years prior). Now presenting with retroperitoneal lymphadenopathy. A retroperitoneal lymph node dissection was performed. Em99

Case 9


5-year-old girl with Swyer syndrome undergoing bilateral gonadectomy. One of the gonads is shown. Em99

Case 10


11-year-old girl undergoing bilateral excisional biopsies of intraabdominal gonads. Em99

Case 11


60-year-old patient with a 5 cm in the right testicle. AFP is 4 ug/L. Em99