Difference between revisions of "DZI19-121-Case-10"

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{{dziSlide
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{{ServiceRequestCase
|order_date=September 11, 2019 01:58:41 PM
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|identifier=DZI19-121-Case-10
|user=Em99
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{{dziCase
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|supportingInfo=Integrated diagnosis:  
|order_date=September 11, 2019 01:58:41 PM
 
|user=Em99
 
|dziorder=DZI19-121
 
|case_id=10
 
|clinical_hx=(ASCP CASE 9) 35 year old woman presents with new onset of tonic-clonic seizures
 
|case_diagnosis=Integrated diagnosis:  
 
 
PLEOMOPHIC XANTHOASTROCYTOMA, BRAF V600E MUTANT
 
PLEOMOPHIC XANTHOASTROCYTOMA, BRAF V600E MUTANT
  
Histological diagnosis: Pleomorphic astrocytoma
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Histological diagnosis: Pleomorphic xanthoastrocytoma
  
 
WHO histological grade: II
 
WHO histological grade: II
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P53: weak in rare tumor cells (immunohistochemistry, consistent with wildtype)
 
P53: weak in rare tumor cells (immunohistochemistry, consistent with wildtype)
 
ATRX: nuclear expression retained (immunohistochemistry, consistent with wildtype)
 
ATRX: nuclear expression retained (immunohistochemistry, consistent with wildtype)
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|reasonCode=(ASCP CASE 9) 35 year old woman presents with new onset of tonic-clonic seizures
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|subject=MGH
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|authoredOn=September 11, 2019 01:58:41 PM
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Latest revision as of 13:23, December 9, 2024

DZI19-121-Case-10
(ASCP CASE 9) 35 year old woman presents with new onset of tonic-clonic seizures
Integrated diagnosis:

PLEOMOPHIC XANTHOASTROCYTOMA, BRAF V600E MUTANT

Histological diagnosis: Pleomorphic xanthoastrocytoma

WHO histological grade: II

Molecular information: BRAF V600E: MUTANT (sequencing) IDH: wildtype (IDH1/2 sequencing) P53: weak in rare tumor cells (immunohistochemistry, consistent with wildtype)

ATRX: nuclear expression retained (immunohistochemistry, consistent with wildtype)
December 31, 1969 7:00:00 PM