Difference between revisions of "DZI19-121-Case-9"

From MGH Learn Pathology
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|order_date=September 11, 2019 01:58:34 PM
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|identifier=DZI19-121-Case-9
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|qctime=Sep 13, 2019 20:41:00
 
|order_date=September 11, 2019 01:58:34 PM
 
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|dziorder=DZI19-121
 
|case_id=9
 
|clinical_hx=(ASCP CASE 8) 19 year old man with dizziness and "clumsiness"
 
|case_diagnosis=Integrated diagnosis:  
 
 
PILOCYTIC ASTROCTYOMA, BRAF-KIAA1549 FUSION POSITIVE  
 
PILOCYTIC ASTROCTYOMA, BRAF-KIAA1549 FUSION POSITIVE  
  
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P53: weak in rare tumor cells (immunohistochemistry, consistent with wildtype)
 
P53: weak in rare tumor cells (immunohistochemistry, consistent with wildtype)
 
ATRX: nuclear expression retained (immunohistochemistry, consistent with wildtype)
 
ATRX: nuclear expression retained (immunohistochemistry, consistent with wildtype)
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|reasonCode=(ASCP CASE 8) 19 year old man with dizziness and "clumsiness"
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Latest revision as of 13:23, December 9, 2024

DZI19-121-Case-9
(ASCP CASE 8) 19 year old man with dizziness and "clumsiness"
Integrated diagnosis:

PILOCYTIC ASTROCTYOMA, BRAF-KIAA1549 FUSION POSITIVE

Histological diagnosis: Pilocytic astrocytoma

WHO histological grade: I

Molecular information: BRAF-KIAA1549 fusion: PRESENT (NGS fusion panel) IDH: wildtype (IDH1/2 sequencing) P53: weak in rare tumor cells (immunohistochemistry, consistent with wildtype)

ATRX: nuclear expression retained (immunohistochemistry, consistent with wildtype)
December 31, 1969 7:00:00 PM